Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | TACR2 | P21452 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17630602 | 0.89 | ADRA2C (0.50) | MEN1USP2GAAKMT2AADRA2C | |
| SCHEMBL23536135 | 0.81 | MEN1 (0.53) | MEN1USP2GAAKMT2AADRA2C | |
| SCHEMBL29948611 | 0.80 | HTT (0.48) | KMT2ANAMPTHTR1ADRD2 | |
| SCHEMBL23536471 | 0.80 | HTT (0.48) | KMT2ANAMPTHTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL4859961 | 0.75 | HTR1A (0.39) | ADRA2CNAMPTHTR1AADRA1DADRA1A | |
| SCHEMBL18046131 | 0.74 | NAMPT (0.43) | ADRA2CNAMPTHTR1AADRA1DADRA1A | |
| SCHEMBL18046134 | 0.74 | NAMPT (0.43) | ADRA2CNAMPTHTR1AADRA1DADRA1A | |
| SCHEMBL23124204 | 0.73 | DRD2 (0.43) | MEN1USP2GAAKMT2AADRA2C | |
| SCHEMBL22542103 | 0.72 | EBP (0.48) | MEN1GAAKMT2AADRA2CHTR1A | |
| SCHEMBL23152040 | 0.72 | ADRA2C (0.79) | MEN1USP2GAAKMT2AADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115087440-A | TRPML modulators | 卡斯玛治疗公司 | 2022-09-20 | — | — | CN | disclosed |