SCHEMBL28869430

SCHEMBL28869430

NS(=O)(=O)c1cc(-c2ccon2)ccc1-c1ccon1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
CA2 P00918 6/20 0.38
CA7 P43166 3/20 0.38
BRD4 O60885 1/20 0.38
BRD2 P25440 1/20 0.38
BRD3 Q15059 1/20 0.38
CA1 P00915 4/20 0.36
CA4 P22748 3/20 0.36
ALOX5AP P20292 4/20 0.35
FEN1 P39748 4/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP19A1 P11511 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
CA12 O43570 3/20 0.35
CA9 Q16790 3/20 0.35
MAOB P27338 2/20 0.34
PTGS2 P35354 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6722914 0.80 PTGS2 (0.46) NPC1RAB9ACA2CA7CA1
SCHEMBL3828659 0.79 CA2 (0.41) CA2CA7CA1CA4ALOX5AP
SCHEMBL27491067 0.75 CA2 (0.34) NPC1RAB9ACA2CA7CA1
SCHEMBL6168789 0.75 CA2 (0.54) CA2CA7CA1CA12CA9
Thiophene SCHEMBL27619739 0.74 CA1 (0.38) NPC1RAB9ACA2CA1CA4
SCHEMBL27536398 0.74 BRD4 (0.31) BRD4BRD2BRD3
SCHEMBL27577517 0.73 CA2 (0.51) CA2CA7CA1CA4CA12
SCHEMBL8890179 0.69 PTPRC (0.31)
SCHEMBL4059081 0.69 CYP1A2 (0.57) NPC1RAB9ACYP1A2CYP2D6CYP19A1
SCHEMBL9825634 0.68 KDM4E (0.35) NPC1RAB9ACA2CA1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109342482-A A kind of flicker detection method, device, X-ray excited polycrystalline structure scintillator and sample collecting apparatus 深圳市福瑞康科技有限公司 2019-02-15 CN claimed