SCHEMBL8890179

SCHEMBL8890179

NS(=O)(=O)c1occc1-c1ccon1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3828659 0.72 CA2 (0.41)
SCHEMBL28010836 0.72 CCNT1 (0.38)
SCHEMBL9825634 0.71 KDM4E (0.35)
SCHEMBL27491067 0.69 CA2 (0.34) PTPRC
SCHEMBL28869430 0.69 NPC1 (0.41)
SCHEMBL6168789 0.68 CA2 (0.54)
SCHEMBL27536398 0.68 BRD4 (0.31)
SCHEMBL7711053 0.66 CA1 (0.39)
SCHEMBL1548721 0.66 POLB (0.52)
SCHEMBL4804428 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5591761-A Thiophenyl-, furyl-and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin TEXAS BIOTECHNOLOGY CORPORATION (US) 1997-01-07 US disclosed