Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ANPEP | P15144 | 2/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28281147 | 0.90 | KDM4E (0.43) | KDM4ETSHRLMNACYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL28870418 | 0.84 | ALDH1A1 (0.40) | KDM4ETSHRALDH1A1CYP3A4KMT2A | |
| SCHEMBL28281121 | 0.81 | CTSL (0.41) | KDM4ELMNACYP1A2CYP2D6SCN1A | |
| SCHEMBL20986435 | 0.78 | KDM4E (0.49) | KDM4ETSHRLMNACYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL20986891 | 0.77 | KDM4E (0.48) | KDM4ETSHRLMNACYP1A2CYP2D6 | |
| SCHEMBL28280069 | 0.77 | KMT2A (0.39) | KDM4EALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL28086157 | 0.74 | LMNA (0.51) | KDM4ETSHRLMNACYP1A2CYP2D6 | |
| SCHEMBL28049253 | 0.74 | LMNA (0.47) | KDM4ETSHRLMNACYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL28314858 | 0.73 | LMNA (0.54) | KDM4ETSHRLMNACYP1A2CYP2D6 | |
| SCHEMBL27999947 | 0.73 | GAA (0.53) | KDM4ETSHRLMNACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415355-A | Benzdioxan derivative and its medicinal usage | 奥赖恩公司 | 2019-03-01 | — | — | CN | disclosed |