Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | MC4R | P32245 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30099606 | 1.00 | NCF1 (0.55) | NCF1ALDH1A1SMN1; SMN2MAPK1KDM4E | |
| SCHEMBL23609528 | 0.77 | DGKA (0.56) | ALDH1A1KDM4EHTR1AHSD17B10NPSR1 | |
| SCHEMBL14139228 | 0.77 | PRKDC (0.54) | NCF1ALDH1A1SMN1; SMN2KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL8880903 | 0.76 | KDR (0.65) | NCF1ALDH1A1MAPK1KDM4EHTR1A | |
| SCHEMBL30616747 | 0.76 | NCF1 (0.43) | NCF1ALDH1A1SMN1; SMN2MAPK1KDM4E | |
| SCHEMBL29137201 | 0.76 | NCF1 (0.43) | NCF1ALDH1A1SMN1; SMN2MAPK1KDM4E | |
| SCHEMBL14044790 | 0.73 | KDM4E (0.50) | ALDH1A1MAPK1KDM4EHPGDALOX15 | |
| SCHEMBL14350002 | 0.72 | LMNA (0.51) | ALDH1A1SMN1; SMN2MAPK1KDM4EHPGD | |
| SCHEMBL3517465 | 0.72 | NCF1 (0.50) | NCF1ALDH1A1SMN1; SMN2HTR1AALOX15 | |
| Hydrochloric Acid SCHEMBL11032993 | 0.72 | DRD2 (0.57) | NCF1ALDH1A1SMN1; SMN2KDM4EDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115103841-A | Substituted quinolinonyl piperazine compounds useful as T cell activators | 百时美施贵宝公司 | 2022-09-23 | — | — | CN | disclosed |