Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30616747 | 1.00 | NCF1 (0.43) | NCF1SIGMAR1HTTTSHRDRD2 | |
| SCHEMBL28550928 | 0.78 | DGKA (0.45) | SIGMAR1HTTTSHRALDH1A1NPSR1 | |
| SCHEMBL29137205 | 0.77 | ALDH1A1 (0.49) | NCF1HTTDRD2HTR1AALDH1A1 | |
| SCHEMBL29137279 | 0.76 | DRD2 (0.43) | NCF1TSHRDRD2HTR1AALDH1A1 | |
| SCHEMBL29137184 | 0.76 | DRD2 (0.40) | NCF1DRD2ALDH1A1DRD4LMNA | |
| SCHEMBL30099606 | 0.76 | NCF1 (0.55) | NCF1SIGMAR1DRD2HTR1AALDH1A1 | |
| SCHEMBL28870573 | 0.76 | NCF1 (0.55) | NCF1SIGMAR1DRD2HTR1AALDH1A1 | |
| SCHEMBL29137283 | 0.75 | DRD4 (0.38) | NCF1SIGMAR1HTR1AALDH1A1DRD4 | |
| SCHEMBL30616673 | 0.75 | SIGMAR1 (0.51) | SIGMAR1TSHRDRD2HTR1AALDH1A1 | |
| SCHEMBL30616711 | 0.74 | GRM2 (0.41) | DRD2HTR1AALDH1A1DRD4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112585139-B | Naphthyridinone compounds as T cell activators | 百时美施贵宝公司 | 2023-12-01 | — | — | CN | disclosed |