Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30257990 | 0.86 | TDP1 (0.56) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL3756498 | 0.86 | TDP1 (0.56) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL29399835 | 0.81 | TDP1 (0.64) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL40706 | 0.81 | ALDH1A1 (0.62) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL6619 | 0.81 | TDP1 (0.64) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL29429960 | 0.81 | ALDH1A1 (0.62) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL29495221 | 0.80 | MAPT (0.59) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL2536509 | 0.80 | MAPT (0.59) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| Ethylene SCHEMBL27608389 | 0.78 | TDP1 (0.60) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL1561802 | 0.77 | TSHR (0.56) | TDP1ATMALDH1A1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113683601-A | Diaza-benzo-fluoranthene compound and preparation method and application thereof | 广东工业大学 | 2021-11-23 | — | — | CN | claimed |
| CN-113683601-B | Diaza-benzo-fluoranthene compound and preparation method and application thereof | 广东工业大学 | 2022-09-20 | — | — | CN | disclosed |
| CN-113683601-A | Diaza-benzo-fluoranthene compound and preparation method and application thereof | 广东工业大学 | 2021-11-23 | — | — | CN | disclosed |