Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.58 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.52 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.52 |
| ▸ | S100A4 | P26447 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29429960 | 1.00 | ALDH1A1 (0.62) | ALDH1A1HIF1AVCAM1AKR1C2AKR1C1 | |
| SCHEMBL6619 | 0.83 | TDP1 (0.64) | ALDH1A1HIF1AVCAM1AKR1C2AKR1C1 | |
| SCHEMBL29399835 | 0.83 | TDP1 (0.64) | ALDH1A1HIF1AVCAM1AKR1C2AKR1C1 | |
| SCHEMBL28871017 | 0.81 | TDP1 (0.50) | ALDH1A1HIF1AVCAM1AKR1C2AKR1C1 | |
| SCHEMBL1561802 | 0.80 | TSHR (0.56) | ALDH1A1S100A4TRPV1ATMTDP1 | |
| Ethylene SCHEMBL27608389 | 0.80 | TDP1 (0.60) | ALDH1A1HIF1AVCAM1AKR1C2AKR1C1 | |
| SCHEMBL12577116 | 0.79 | ALDH1A1 (0.38) | ALDH1A1HIF1AVCAM1AKR1C2AKR1C1 | |
| SCHEMBL204357 | 0.78 | S100A4 (0.61) | ALDH1A1S100A4TRPV1MAPTMAPK1 | |
| SCHEMBL29395434 | 0.78 | S100A4 (0.56) | ALDH1A1S100A4TRPV1MAPTLMNA | |
| SCHEMBL11579276 | 0.78 | ALDH1A1 (0.67) | ALDH1A1HIF1AVCAM1ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2544 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122079918-A | Isoxazole biphenyl compounds with CBP BRD and BRD4 BD2 inhibitory activity, and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-117362277-B | Benzamide compound containing imidazolone structure, and preparation method and application thereof | 沈阳药科大学 | 2025-02-11 | — | — | CN | claimed |
| CN-117362277-A | Benzamide compound containing imidazolone structure, and preparation method and application thereof | 沈阳药科大学 | 2024-01-09 | — | — | CN | claimed |
| CN-112500260-B | Preparation method of 2-fluoro-5-bromoiodobenzene | 山东瑞辰新材料有限公司 | 2022-12-27 | — | — | CN | claimed |
| CN-111153846-B | Pyrrole compound, preparation method thereof, pharmaceutical composition and application | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2021-08-31 | — | — | CN | claimed |
| WO-2021143936-A1 | INDOLE COMPOUNDS, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 中国药科大学 | 2021-07-22 | — | — | WO | claimed |
| WO-2021143937-A1 | PYRROLE COMPOUNDS, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 中国药科大学 | 2021-07-22 | — | — | WO | claimed |
| CN-112500260-A | Preparation method of 2-fluoro-5-bromoiodobenzene | 山东瑞辰新材料有限公司 | 2021-03-16 | — | — | CN | claimed |
| US-10703764-B2 | Benzopiperazine compositions as BET bromodomain inhibitors | FORMA THERAPEUTICS, INC. (US) | 2020-07-07 | — | — | US | claimed |
| CN-111153850-A | Indole compound, preparation method thereof, pharmaceutical composition and application | 中国药科大学 | 2020-05-15 | — | — | CN | claimed |
| CN-104530107-A | Synthetic method for 3-amino-4-fluorophenylboronic acid | LIANHUA CHEMISTRY CO LTD DALIAN | 2015-04-22 | — | — | CN | claimed |
| EP-2445345-B1 | BENZAMIDE DERIVATIVES | TRANSLATIONAL GENOMICS RES INST (US) | 2014-08-27 | — | — | EP | claimed |
| US-20120142922-A1 | BENZAMIDE DERIVATIVES | TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (US) | 2012-06-07 | — | — | US | claimed |
| EP-2445345-A1 | BENZAMIDE DERIVATIVES | The Translational Genomics Research Institute (US) | 2012-05-02 | — | — | EP | claimed |
| CN-101445460-B | Method for preparing 2-fluoride-5-alkoxyl aniline | BINHAI KANGJIE CHEMICAL CO LTD | 2011-11-16 | — | — | CN | claimed |
| CN-101450906-B | Method for preparing 3-amino-4-fluorophenol | TAIXING CHEMSPEC CHEMICALS CO LTD | 2011-06-22 | — | — | CN | claimed |
| WO-2010151441-A1 | BENZAMIDE DERIVATIVES | TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (US) | 2010-12-29 | — | — | WO | claimed |
| CN-101450906-A | Method for preparing 3-amino-4-fluorophenol | TAIXING KANGPENG CHEMICALS CO (CN) | 2009-06-10 | — | — | CN | claimed |
| CN-101445460-A | Method for preparing 2-fluoride-5-alkoxyl aniline | BINHAI KANGJIE CHEMICAL CO LTD (CN) | 2009-06-03 | — | — | CN | claimed |
| WO-2009002955-A1 | PROCESS FOR THE PREPARATION OF (2R)-2-[4-(7-BROMO-2-QUINOLYLOXY)PHENOXY]PROPANOIC ACID | SANOFI-AVENTIS U.S. LLC (US) | 2008-12-31 | — | — | WO | claimed |