Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | UBE2N | P61088 | 1/20 | 0.32 |
| ▸ | GPR6 | P46095 | 2/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29395256 | 0.86 | SIGMAR1 (0.42) | SIGMAR1 | |
| SCHEMBL5333364 | 0.86 | SIGMAR1 (0.42) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL5740537 | 0.84 | SIGMAR1 (0.41) | SIGMAR1 | |
| SCHEMBL2007099 | 0.72 | SIGMAR1 (0.42) | KDM4EALDH1A1KDM4CSIGMAR1 | |
| Trifluoroacetic Acid SCHEMBL30343298 | 0.68 | CHRNB2 (0.56) | KDM1ASIGMAR1 | |
| Trifluoroacetic Acid SCHEMBL30343227 | 0.67 | L3MBTL1 (0.42) | L3MBTL1SLC22A12KDM4EMEN1KDM6B | |
| SCHEMBL19447878 | 0.65 | CYP11B2 (0.46) | SIGMAR1 | |
| SCHEMBL15559911 | 0.65 | KDM4C (0.38) | L3MBTL1KDM4EMEN1KDM6BKDM4A | |
| Trifluoroacetic Acid SCHEMBL6513879 | 0.65 | L3MBTL1 (0.32) | KDM1AL3MBTL1SLC22A12ELANE | |
| SCHEMBL30130240 | 0.64 | SIGMAR1 (0.36) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115087486-A | Substituted bicyclic and tricyclic ureas and amides, analogs thereof, and methods of use thereof | 爱彼特生物制药公司 | 2022-09-20 | — | — | CN | disclosed |