SCHEMBL2887218

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15267406	0.88	PTGS2 (0.57)	PTGS2HSD17B10KDM4ELMNACYP1A2
	SCHEMBL14714206	0.84	MAPT (0.46)	PTGS2HSD17B10KDM4ELMNACYP1A2
	Phenylaspirinate SCHEMBL25954	0.81	HSD17B10 (0.75)	PTGS2HSD17B10KDM4ELMNACYP1A2
	Phenylaspirinate SCHEMBL29389369	0.81	HSD17B10 (0.75)	PTGS2HSD17B10KDM4ELMNACYP1A2
	SCHEMBL3419623	0.81	LMNA (0.53)	HSD17B10KDM4ELMNAALDH1A1ESR1
	SCHEMBL11929659	0.80	PTGS2 (0.57)	PTGS2HSD17B10KDM4ELMNACYP1A2
	SCHEMBL21449134	0.80	PTGS2 (0.68)	PTGS2HSD17B10KDM4ELMNACYP1A2
	SCHEMBL15267403	0.79	PTGS2 (0.63)	PTGS2HSD17B10KDM4ELMNACYP1A2
	SCHEMBL14714209	0.78	MAPT (0.41)	PTGS2HSD17B10KDM4ELMNACYP1A2
	SCHEMBL11925078	0.77	PTGS2 (0.54)	PTGS2HSD17B10KDM4ELMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.