Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.39 |
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 3/20 | 0.38 |
| ▸ | CES1 | P23141 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27983508 | 1.00 | PRKCA (0.46) | PRKCALMNAALDH1A1MAPTHPGD | |
| SCHEMBL1935917 | 1.00 | PRKCA (0.46) | PRKCALMNAALDH1A1MAPTHPGD | |
| SCHEMBL27309683 | 0.98 | PRKCA (0.43) | PRKCALMNAALDH1A1MAPTHPGD | |
| Ammonia Solution, Strong SCHEMBL28872308 | 0.97 | PRKCA (0.42) | PRKCALMNAALDH1A1MAPTHPGD | |
| SCHEMBL8192444 | 0.87 | LMNA (0.39) | PRKCALMNAALDH1A1MAPTHPGD | |
| SCHEMBL1133829 | 0.84 | ALDH1A1 (0.40) | PRKCALMNAALDH1A1MAPTHPGD | |
| SCHEMBL5061804 | 0.79 | BRD4 (0.33) | — | |
| SCHEMBL129229 | 0.78 | PTGS1 (0.53) | LMNAALDH1A1MAPTHPGDHTT | |
| SCHEMBL27689659 | 0.78 | ALDH1A1 (0.38) | PRKCALMNAALDH1A1MAPTHPGD | |
| SCHEMBL7824143 | 0.78 | PRKCA (0.51) | PRKCALMNAALDH1A1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202748-B1 | POLYCATION-BASED BIOCONJUGATES | SZEGOE PETER (HU) | 2008-09-17 | — | — | EP | disclosed |
| US-7090846-B2 | Method for preparing polycation based bioconjugates suitable for transporting different kinds of active substances within the body | REFUAH RESEARCH, INC. (US) | 2006-08-15 | — | — | US | disclosed |
| US-20040220083-A1 | Method for preparing polycation based bioconjugates suitable for transporting different kinds of active substances within the body | REFUAH RESEARCH, INC. | 2004-11-04 | — | — | US | disclosed |
| US-6727347-B1 | USED TO INHIBIT MALIGNANT CELL PROLIFERATION, POSSESS ANTIMICROBIAL EFFECT, OR GENE TRANSPORT CONFIGURATION | REFUAH RESEARCH, INC. | 2004-04-27 | — | — | US | disclosed |
| EP-1202748-A2 | POLYCATION-BASED BIOCONJUGATES | Szeg&Odblac, Péter (HU) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001000242-A2 | POLYCATION-BASED BIOCONJUGATES | SZEGOE PETER (HU) | 2001-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220083-A1 | Method for preparing polycation based bioconjugates suitable for transporting different kinds of active substances within the body | ABCB11, SLC47A1, SLC67A1 | PRKCA 3972/4885LMNA 3340/4885ALDH1A1 1561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.