Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TNKS | O95271 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6368201 | 0.79 | NPC1 (0.55) | NPC1RAB9AGAAMAPTTNKS | |
| SCHEMBL10212238 | 0.78 | DHODH (0.64) | DHODH | |
| SCHEMBL5204651 | 0.76 | PTGES (0.45) | GAADHODH | |
| SCHEMBL3336231 | 0.75 | NPC1 (0.62) | NPC1RAB9AGAAMAPTTNKS | |
| SCHEMBL6373232 | 0.75 | NPC1 (0.49) | NPC1RAB9AGAAMAPTTNKS | |
| SCHEMBL29899918 | 0.73 | RPS6KA3 (0.72) | GAARPS6KA3DHODH | |
| SCHEMBL28872962 | 0.73 | RPS6KA3 (0.72) | GAARPS6KA3DHODH | |
| SCHEMBL3337332 | 0.72 | METAP2 (0.62) | NPC1RAB9AGAAMAPTKDM4E | |
| SCHEMBL5850166 | 0.72 | PARP1 (0.43) | NPC1RAB9AGAAMAPTPARP1 | |
| SCHEMBL276208 | 0.71 | NPC1 (0.73) | NPC1RAB9AGAAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106866543-B | A method of benzimidazole compound is catalyzed and synthesized under microwave radiation in water phase | 福建医科大学 | 2019-05-14 | — | — | CN | disclosed |