Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL151433 | 0.79 | ALDH1A1 (0.37) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| SCHEMBL16028759 | 0.74 | — | — | |
| SCHEMBL23092079 | 0.74 | ALOX15 (0.42) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| SCHEMBL29240420 | 0.72 | ALOX15 (0.40) | ALOX15ALDH1A1LMNAHSD17B10 | |
| SCHEMBL27462342 | 0.72 | — | — | |
| SCHEMBL13698699 | 0.72 | — | — | |
| SCHEMBL3393438 | 0.72 | DGAT1 (0.40) | ALOX15 | |
| SCHEMBL4283572 | 0.70 | ALOX15 (0.39) | ALOX15ALDH1A1 | |
| SCHEMBL2171395 | 0.70 | ALOX15 (0.39) | ALOX15ALDH1A1LMNAHSD17B10PARP10 | |
| SCHEMBL17652006 | 0.70 | ALOX15 (0.39) | ALOX15ALDH1A1LMNAHSD17B10PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110214012-A | Azole pyrimidines for the treatment of cancer-related diseases | 艾库斯生物科学有限公司 | 2019-09-06 | — | — | CN | disclosed |
| CN-110049767-A | Inhibitors of adenosine 5' -nucleotidase | 艾库斯生物科学有限公司 | 2019-07-23 | — | — | CN | disclosed |