SCHEMBL4283572

SCHEMBL4283572

CCOC(OC)(OCC)C(N)=O

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.39
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20641576 0.79 LMNA (0.35) ALOX15ALDH1A1
SCHEMBL2162997 0.78 ALDH1A1 (0.32) ALDH1A1
SCHEMBL223597 0.78 ALDH1A1 (0.32) ALDH1A1
SCHEMBL22863849 0.76 DGAT1 (0.33) ALDH1A1
SCHEMBL5859305 0.74
SCHEMBL10542829 0.74 ALDH1A1 (0.39) ALOX15ALDH1A1
SCHEMBL23092079 0.70 ALOX15 (0.42) ALOX15ALDH1A1
SCHEMBL16028759 0.70
SCHEMBL15951338 0.70 MGAM (0.36) ALOX15ALDH1A1
SCHEMBL28875134 0.70 ALOX15 (0.42) ALOX15ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090192192-A1 INHIBITORS OF BIOFILM FORMATION OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA TOUCH BIONICS LIMITED (GB) 2009-07-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090192192-A1 INHIBITORS OF BIOFILM FORMATION OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA PGLS, TFPI, Q6ZSR9 ALOX15 3970/4885ALDH1A1 4657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.