Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | COMT | P21964 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28312419 | 0.87 | HTR6 (0.41) | KMT2AGAAHSD11B1CNR2TP53 | |
| SCHEMBL30394693 | 0.86 | FEN1 (0.41) | KMT2ARXFP1TP53FEN1 | |
| SCHEMBL29057999 | 0.86 | FEN1 (0.41) | KMT2ARXFP1TP53FEN1 | |
| SCHEMBL29058023 | 0.86 | ALDH1A1 (0.41) | MEN1KMT2AHSD11B1CNR2ALDH1A1 | |
| SCHEMBL28311435 | 0.86 | FEN1 (0.36) | MEN1KMT2AHSD11B1CNR2ALDH1A1 | |
| SCHEMBL30394770 | 0.86 | FEN1 (0.36) | MEN1KMT2AHSD11B1CNR2ALDH1A1 | |
| SCHEMBL29057934 | 0.85 | PKM (0.48) | GAAHSD11B1ALDH1A1RXFP1 | |
| SCHEMBL29057921 | 0.84 | HSD11B1 (0.45) | COMTHSD11B1CNR2ALDH1A1CNR1 | |
| SCHEMBL29057909 | 0.83 | EPHX2 (0.38) | KMT2AGAACNR2KDM4EALDH1A1 | |
| SCHEMBL29057943 | 0.78 | NFE2L2 (0.41) | MEN1KMT2AHSD11B1ALDH1A1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110117264-B | Phenyl sulfone derivative and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-110117264-A | Phenyl sulfone derivative and its application on drug | 广东东阳光药业有限公司 | 2019-08-13 | — | — | CN | disclosed |