Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6ST | P40189 | 5/20 | 0.53 |
| ▸ | FAAH | O00519 | 9/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 3/20 | 0.38 |
| ▸ | IDH1 | O75874 | 4/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2887710 | 0.91 | IL6ST (0.54) | IL6STFAAHSTAT3MGLLIDH1 | |
| SCHEMBL2887707 | 0.91 | IL6ST (0.54) | IL6STFAAHSTAT3MGLLIDH1 | |
| SCHEMBL7321939 | 0.82 | IL6ST (0.59) | IL6STSTAT3IDH1NAAA | |
| SCHEMBL7321930 | 0.82 | IL6ST (0.59) | IL6STSTAT3IDH1NAAA | |
| SCHEMBL7438121 | 0.82 | IL6ST (0.59) | IL6STSTAT3IDH1NAAA | |
| SCHEMBL30984038 | 0.80 | IL6ST (0.56) | IL6STFAAHSTAT3IDH1NAAA | |
| SCHEMBL2070699 | 0.78 | IL6ST (0.54) | IL6STFAAHSTAT3IDH1NAAA | |
| SCHEMBL6601336 | 0.78 | IL6ST (0.54) | IL6STFAAHSTAT3IDH1NAAA | |
| SCHEMBL7359508 | 0.78 | IL6ST (0.55) | IL6STFAAHSTAT3IDH1NAAA | |
| SCHEMBL7359514 | 0.78 | IL6ST (0.55) | IL6STFAAHSTAT3IDH1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070167452-A1 | Therapeutic amide derivatives | PFIZER, INC. | 2007-07-19 | — | — | US | disclosed |
| US-20070167452-A1 | Therapeutic amide derivatives | PFIZER, INC. | 2007-07-19 | — | — | US | disclosed |
| US-20070167452-A1 | Therapeutic amide derivatives | PFIZER, INC. | 2007-07-19 | — | — | US | disclosed |
| WO-2005080317-A2 | THERAPEUTIC AMIDE DERIVATIVES | PFIZER JAPAN, INC. (JP) | 2005-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167452-A1 | Therapeutic amide derivatives | GRIN1, GRIN2B, GRIN3A | IL6ST 621/4885FAAH 278/4885STAT3 1473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.