Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28877273 | 0.82 | ABCC8 (0.35) | ABCC8KCNJ11ALOX5APFEN1MPL | |
| SCHEMBL29947822 | 0.82 | ABCC8 (0.44) | ABCC8KCNJ11ALOX5APFEN1KCNH2 | |
| SCHEMBL28877253 | 0.79 | KDM4E (0.38) | ABCC8KCNJ11ALOX5APFEN1 | |
| SCHEMBL28877271 | 0.78 | ADORA2A (0.42) | ABCC8KCNJ11ALOX5APFEN1KCNH2 | |
| SCHEMBL28877259 | 0.77 | MPL (0.34) | ABCC8KCNJ11ALOX5APFEN1KCNH2 | |
| SCHEMBL28877294 | 0.74 | ADORA2A (0.39) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL28877270 | 0.72 | PIK3CA (0.38) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL24003191 | 0.70 | APP (0.38) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL24003193 | 0.67 | PIK3CD (0.34) | PDE3BPDE3APIK3CDPIK3CAPIK3CB | |
| SCHEMBL5934872 | 0.67 | CYP19A1 (0.45) | PDE3BPDE3APIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260245-A | Iridium metal complex, application thereof and organic electroluminescent device | 清华大学 | 2022-11-01 | — | — | CN | disclosed |