Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC8 | Q09428 | 1/20 | 0.44 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.40 |
| ▸ | FEN1 | P39748 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | IL1B | P01584 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MPL | P40238 | 1/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SLC9A5 | Q14940 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28877271 | 0.90 | ADORA2A (0.42) | ABCC8KCNJ11ALOX5APFEN1GAA | |
| SCHEMBL28877253 | 0.85 | KDM4E (0.38) | ABCC8KCNJ11ALOX5APFEN1GAA | |
| SCHEMBL28877261 | 0.82 | PDE3B (0.40) | ABCC8KCNJ11ALOX5APFEN1MPL | |
| SCHEMBL28877273 | 0.82 | ABCC8 (0.35) | ABCC8KCNJ11ALOX5APFEN1MPL | |
| SCHEMBL28877259 | 0.81 | MPL (0.34) | ABCC8KCNJ11ALOX5APFEN1MPL | |
| SCHEMBL28676412 | 0.75 | TSHR (0.56) | ABCC8KCNJ11ALOX5APFEN1CES2 | |
| SCHEMBL29947885 | 0.73 | MKNK1 (0.47) | MAOBKDM4E | |
| SCHEMBL19072706 | 0.71 | ALOX5AP (0.44) | ABCC8KCNJ11ALOX5APFEN1KCNH2 | |
| SCHEMBL19072709 | 0.70 | TRPV1 (0.51) | ABCC8KCNJ11 | |
| SCHEMBL26375518 | 0.69 | ABCC8 (0.43) | ABCC8KCNJ11ALOX5APFEN1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260245-A | Iridium metal complex, application thereof and organic electroluminescent device | 清华大学 | 2022-11-01 | — | — | CN | disclosed |