Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 3/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | EIF4E | P06730 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29947822 | 0.81 | ABCC8 (0.44) | MPLHSD11B1ABCC8KCNJ11ALOX5AP | |
| SCHEMBL28877271 | 0.78 | ADORA2A (0.42) | ABCC8KCNJ11ALOX5APFEN1KCNH2 | |
| SCHEMBL28877261 | 0.77 | PDE3B (0.40) | MPLABCC8KCNJ11ALOX5APFEN1 | |
| SCHEMBL28877253 | 0.76 | KDM4E (0.38) | ABCC8KCNJ11ALOX5APFEN1 | |
| SCHEMBL28877292 | 0.74 | — | — | |
| SCHEMBL28877289 | 0.71 | CYP11B1 (0.39) | HSD11B1ABCC8KCNJ11ALOX5APFEN1 | |
| SCHEMBL28877266 | 0.71 | CHEK1 (0.31) | MAPK14 | |
| SCHEMBL28877273 | 0.70 | ABCC8 (0.35) | MPLABCC8KCNJ11ALOX5APFEN1 | |
| SCHEMBL11976481 | 0.70 | CNR2 (0.46) | ABCC8KCNJ11ALOX5APFEN1 | |
| SCHEMBL28465389 | 0.68 | ADORA2A (0.45) | ABCC8KCNJ11ALOX5APFEN1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260245-A | Iridium metal complex, application thereof and organic electroluminescent device | 清华大学 | 2022-11-01 | — | — | CN | disclosed |