Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 12/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM5A | P29375 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5532401 | 0.82 | DHODH (0.49) | DHODHKMT2A | |
| SCHEMBL3935826 | 0.74 | KDM4E (0.61) | TRPV1KDM4EALDH1A1KMT2A | |
| SCHEMBL29085964 | 0.74 | GLRA3 (0.36) | KDM4EALDH1A1KMT2AKDM5AKDM5B | |
| SCHEMBL22712444 | 0.70 | RAB9A (0.50) | DHODHKDM4EALDH1A1KMT2ASRD5A2 | |
| SCHEMBL27907482 | 0.70 | MEN1 (0.54) | DHODHKDM4EALDH1A1KMT2A | |
| SCHEMBL2858513 | 0.70 | DHODH (0.44) | TRPV1DHODHKDM4C | |
| SCHEMBL28052040 | 0.70 | KDM4E (0.54) | TRPV1KDM4EALDH1A1KMT2A | |
| SCHEMBL353204 | 0.69 | KDM4E (0.40) | KDM4EALDH1A1KMT2AKDM5AKDM4C | |
| SCHEMBL22712424 | 0.69 | RAB9A (0.49) | DHODHKDM4EALDH1A1KMT2ASRD5A2 | |
| SCHEMBL645855 | 0.69 | KDM4E (0.49) | DHODHKDM4EALDH1A1KMT2AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110520413-A | Big ring broad-spectrum antibiotic | RQX PHARMACEUTICALS INC | 2019-11-29 | — | — | CN | disclosed |