Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | NOS3 | P29474 | 5/20 | 0.47 |
| ▸ | NOS1 | P29475 | 5/20 | 0.47 |
| ▸ | NOS2 | P35228 | 5/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1072482 | 1.00 | KMT2A (0.55) | KMT2AMEN1NOS3NOS1NOS2 | |
| SCHEMBL22122444 | 1.00 | KMT2A (0.55) | KMT2AMEN1NOS3NOS1NOS2 | |
| SCHEMBL5527768 | 0.81 | KMT2A (0.55) | KMT2AMEN1KDM4EMAPTTSHR | |
| SCHEMBL29482763 | 0.79 | CTNNB1 (0.59) | KMT2AMEN1NOS3NOS1NOS2 | |
| SCHEMBL93515 | 0.79 | CTNNB1 (0.59) | KMT2AMEN1NOS3NOS1NOS2 | |
| SCHEMBL660499 | 0.79 | CTNNB1 (0.59) | KMT2AMEN1NOS3NOS1NOS2 | |
| SCHEMBL29397858 | 0.79 | CTNNB1 (0.59) | KMT2AMEN1NOS3NOS1NOS2 | |
| SCHEMBL93516 | 0.79 | CTNNB1 (0.59) | KMT2AMEN1NOS3NOS1NOS2 | |
| SCHEMBL29397866 | 0.79 | CTNNB1 (0.59) | KMT2AMEN1NOS3NOS1NOS2 | |
| Pyrene SCHEMBL28205462 | 0.79 | SLC7A5 (0.76) | NOS3NOS1NOS2PKMALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106967213-B | Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance | 厦门赛诺邦格生物科技股份有限公司 | 2019-11-05 | — | — | CN | disclosed |