SCHEMBL22122444

SCHEMBL22122444

NC(Cc1ccc2ccc3cccc4ccc1c2c34)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 4/20 0.55
▸ MEN1 O00255 3/20 0.55
▸ NOS3 P29474 5/20 0.47
▸ NOS1 P29475 5/20 0.47
▸ NOS2 P35228 5/20 0.47
▸ PKM P14618 2/20 0.46
▸ ALPI P09923 1/20 0.46
▸ PTGS1 P23219 1/20 0.46
▸ XIAP P98170 1/20 0.46
▸ SLC7A5 Q01650 1/20 0.46
▸ KDM4E B2RXH2 4/20 0.46
▸ MAPT P10636 3/20 0.46
▸ LMNA P02545 2/20 0.46
▸ BLM P54132 2/20 0.46
▸ PMP22 Q01453 2/20 0.46
▸ HIF1A Q16665 2/20 0.46
▸ MPO P05164 1/20 0.46
▸ TSHR P16473 1/20 0.46
▸ ALDH1A1 P00352 4/20 0.45
▸ RECQL P46063 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28879239 1.00 KMT2A (0.55) KMT2AMEN1NOS3NOS1NOS2
SCHEMBL1072482 1.00 KMT2A (0.55) KMT2AMEN1NOS3NOS1NOS2
SCHEMBL5527768 0.81 KMT2A (0.55) KMT2AMEN1KDM4EMAPTTSHR
SCHEMBL29482763 0.79 CTNNB1 (0.59) KMT2AMEN1NOS3NOS1NOS2
SCHEMBL93515 0.79 CTNNB1 (0.59) KMT2AMEN1NOS3NOS1NOS2
SCHEMBL660499 0.79 CTNNB1 (0.59) KMT2AMEN1NOS3NOS1NOS2
SCHEMBL29397858 0.79 CTNNB1 (0.59) KMT2AMEN1NOS3NOS1NOS2
SCHEMBL93516 0.79 CTNNB1 (0.59) KMT2AMEN1NOS3NOS1NOS2
SCHEMBL29397866 0.79 CTNNB1 (0.59) KMT2AMEN1NOS3NOS1NOS2
Pyrene SCHEMBL28205462 0.79 SLC7A5 (0.76) NOS3NOS1NOS2PKMALPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12616761-B2 CXCR4-targeting compounds THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2026-05-05 — — US disclosed
US-20260077073-A1 GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR)-TARGETED COMPOUNDS AND USES THEREOF ALPHA 9 ONCOLOGY INC (CA) 2026-03-19 — — US disclosed
US-12514939-B2 Stable radiopharmaceutical compositions and uses thereof ALPHA-9 ONCOLOGY, INC. (CA) 2026-01-06 — — US disclosed
US-12472272-B2 Radiolabelled compounds for diagnosis or treatment of prostate-specific membrane antigen- expressing cancer PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2025-11-18 — — US disclosed
US-12427209-B2 Dual mode 18F-labelled theranostic compounds and uses thereof PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2025-09-30 — — US disclosed
US-20250255993-A1 STABLE RADIOPHARMACEUTICAL COMPOSITIONS AND USES THEREOF ALPHA-9 ONCOLOGY INC. (CA) 2025-08-14 — — US disclosed
US-20250242064-A1 CXCR4-TARGETING COMPOUNDS, AND METHODS OF MAKING AND USING THE SAME ALPHA-9 ONCOLOGY INC. (CA) 2025-07-31 — — US disclosed
US-20250195702-A1 RADIOLABELED COMPOUNDS FOR IN VIVO IMAGING OF GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR) AND TREATMENT OF GRPR-RELATED DISORDERS PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2025-06-19 — — US disclosed
US-20250186627-A1 RADIOLABELED COMPOUNDS TARGETING THE PROSTATE-SPECIFIC MEMBRANE ANTIGEN PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2025-06-12 — — US disclosed
CN-120081907-A Radiolabeled bombesin derivative compounds for in vivo imaging of the Gastrin Releasing Peptide Receptor (GRPR) and treatment of GRPR-related disorders 省卫生服务机构 2025-06-03 — — CN disclosed
US-20210402016-A1 RADIOLABELED BOMBESIN-DERIVED COMPOUNDS FOR IN VIVO IMAGING OF GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR) AND TREATMENT OF GRPR-RELATED DISORDERS PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2021-12-30 — — US disclosed
US-20210338851-A1 RADIOLABELED COMPOUNDS TARGETING THE PROSTATE-SPECIFIC MEMBRANE ANTIGEN THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2021-11-04 — — US disclosed
EP-3897751-A1 <SUP2/>? <SUB2/>?18? ?DUAL MODEF-LABELLED THERANOSTIC COMPOUNDS AND USES THEREOF Provincial Health Services Authority (CA) 2021-10-27 — — EP disclosed
CN-113454098-A Radiolabeled bombesin derivative compounds for in vivo imaging of Gastrin Releasing Peptide Receptor (GRPR) and treatment of GRPR related disorders 省卫生服务机构 2021-09-28 — — CN disclosed
EP-3880691-A1 RADIOLABELED BOMBESIN-DERIVED COMPOUNDS FOR IN VIVO IMAGING OF GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR) AND TREATMENT OF GRPR-RELATED DISORDERS Provincial Health Services Authority (CA) 2021-09-22 — — EP disclosed
WO-2021068051-A1 RADIOLABELED BOMBESIN-DERIVED COMPOUNDS FOR IN VIVO IMAGING OF GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR) AND TREATMENT OF GRPR-RELATED DISORDERS PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2021-04-15 — — WO disclosed
WO-2020252598-A1 RADIOLABELED COMPOUNDS TARGETING THE PROSTATE-SPECIFIC MEMBRANE ANTIGEN PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2020-12-24 — — WO disclosed
WO-2020210919-A1 NOVEL RADIOLABELLED CXCR4-TARGETING COMPOUNDS FOR DIAGNOSIS AND THERAPY PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2020-10-22 — — WO disclosed
WO-2020210909-A1 NOVEL RADIOLABELLED COMPOUNDS FOR DIAGNOSIS OR TREATMENT OF PROSTATE-SPECIFIC MEMBRANE ANTIGEN-EXPRESSING CANCER PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2020-10-22 — — WO disclosed
WO-2020124237-A1 DUAL MODE 18F-LABELLED THERANOSTIC COMPOUNDS AND USES THEREOF PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2020-06-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250242064-A1 CXCR4-TARGETING COMPOUNDS, AND METHODS OF MAKING AND USING THE SAME CXCR4, CXCL12, ACKR3 KMT2A 4385/4885MEN1 2317/4885NOS3 3411/4885
US-20210338851-A1 RADIOLABELED COMPOUNDS TARGETING THE PROSTATE-SPECIFIC MEMBRANE ANTIGEN FOLH1, KLK3, PSMA3 KMT2A 1402/4885MEN1 75/4885NOS3 1755/4885
US-20250186627-A1 RADIOLABELED COMPOUNDS TARGETING THE PROSTATE-SPECIFIC MEMBRANE ANTIGEN FSHR, ESRRA, ESRRG KMT2A 3795/4885MEN1 1094/4885NOS3 4479/4885
US-12427209-B2 Dual mode 18F-labelled theranostic compounds and uses thereof TFRC, SLC39A3, SLC39A14 KMT2A 2434/4885MEN1 79/4885NOS3 4384/4885
US-20250255993-A1 STABLE RADIOPHARMACEUTICAL COMPOSITIONS AND USES THEREOF RCN1, RABL6, QPCT KMT2A 3065/4885MEN1 193/4885NOS3 4202/4885
US-12616761-B2 CXCR4-targeting compounds CXCR4, CXCR2, CXCR3 KMT2A 3174/4885MEN1 3462/4885NOS3 2987/4885
US-12472272-B2 Radiolabelled compounds for diagnosis or treatment of prostate-specific membrane antigen- expressing cancer KLK3, FOLH1, HRH3 KMT2A 484/4885MEN1 423/4885NOS3 2689/4885
US-20210402016-A1 RADIOLABELED BOMBESIN-DERIVED COMPOUNDS FOR IN VIVO IMAGING OF GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR) AND TREATMENT OF GRPR-RELATED DISORDERS GRPR, NPY1R, GIPR KMT2A 3383/4885MEN1 943/4885NOS3 1559/4885
US-20250195702-A1 RADIOLABELED COMPOUNDS FOR IN VIVO IMAGING OF GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR) AND TREATMENT OF GRPR-RELATED DISORDERS GRPR, NPY5R, NPY2R KMT2A 1870/4885MEN1 708/4885NOS3 4059/4885
US-20260077073-A1 GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR)-TARGETED COMPOUNDS AND USES THEREOF GRPR, GIPR, GLP1R KMT2A 4091/4885MEN1 901/4885NOS3 4003/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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