Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | NOS3 | P29474 | 5/20 | 0.47 |
| ▸ | NOS1 | P29475 | 5/20 | 0.47 |
| ▸ | NOS2 | P35228 | 5/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28879239 | 1.00 | KMT2A (0.55) | KMT2AMEN1NOS3NOS1NOS2 | |
| SCHEMBL22122444 | 1.00 | KMT2A (0.55) | KMT2AMEN1NOS3NOS1NOS2 | |
| SCHEMBL5527768 | 0.81 | KMT2A (0.55) | KMT2AMEN1KDM4EMAPTTSHR | |
| SCHEMBL29482763 | 0.79 | CTNNB1 (0.59) | KMT2AMEN1NOS3NOS1NOS2 | |
| SCHEMBL93515 | 0.79 | CTNNB1 (0.59) | KMT2AMEN1NOS3NOS1NOS2 | |
| SCHEMBL660499 | 0.79 | CTNNB1 (0.59) | KMT2AMEN1NOS3NOS1NOS2 | |
| SCHEMBL29397858 | 0.79 | CTNNB1 (0.59) | KMT2AMEN1NOS3NOS1NOS2 | |
| SCHEMBL93516 | 0.79 | CTNNB1 (0.59) | KMT2AMEN1NOS3NOS1NOS2 | |
| SCHEMBL29397866 | 0.79 | CTNNB1 (0.59) | KMT2AMEN1NOS3NOS1NOS2 | |
| Pyrene SCHEMBL28205462 | 0.79 | SLC7A5 (0.76) | NOS3NOS1NOS2PKMALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170370916-A1 | HIGH-SENSITIVE FLUORESCENT ENERGY TRANSFER ASSAY USING FLUORESCENT AMINO ACIDS AND FLUORESCENT PROTEINS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-12-28 | — | — | US | disclosed |
| US-20150369800-A1 | HIGH-SENSITIVE FLUORESCENT ENERGY TRANSFER ASSAY USING FLUORESCENT AMINO ACIDS AND FLUORESENT PROTEINS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-12-24 | — | — | US | disclosed |
| WO-2015175941-A1 | CYSTEINE ARYLATION DIRECTED BY A GENETICALLY ENCODABLE π-CLAMP | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-11-19 | — | — | WO | disclosed |
| US-8940506-B2 | High-sensitive fluorescent energy transfer assay using fluoresent amino acids and fluorescent proteins | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-01-27 | — | — | US | disclosed |
| US-20110117556-A1 | HIGH-SENSITIVE FLUORESCENT ENERGY TRANSFER ASSAY USING FLUORESCENT AMINO ACIDS AND FLUORESENT PROTEINS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-05-19 | — | — | US | disclosed |
| EP-2271662-A2 | HIGH-SENSITIVE FLUORESCENT ENERGY TRANSFER ASSAY USING FLUORESCENT AMINO ACIDS AND FLUORESENT PROTEINS | The Regents Of The University Of California (US) | 2011-01-12 | — | — | EP | disclosed |
| WO-2009117726-A2 | HIGH-SENSITIVE FLUORESCENT ENERGY TRANSFER ASSAY USING FLUORESCENT AMINO ACIDS AND FLUORESENT PROTEINS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-09-24 | — | — | WO | disclosed |
| US-20070161807-A1 | Method for manufacturing optically pure coumaryl amino acids and the novel coumaryl aminoacids thus obtained | INSERM (INSTITUT NATIONAL DE LA SANT'E ET DE LA RECHERCHE MEDICALE (FR) | 2007-07-12 | — | — | US | disclosed |
| EP-1711483-A2 | A METHOD FOR MANUFACTURING OPTICALLY PURE COUMARYL AMINO ACID SALTS AND THE COUMARYL AMINO ACID SALTS THUS OBTAINED | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2006-10-18 | — | — | EP | disclosed |
| WO-2005075448-A2 | A METHOD FOR MANUFACTURING OPTICALLY PURE COUMARYL AMINO ACIDS SALTS AND THE COUMARYL AMINO ACID SALTS THUS OBTAINED | INSTITUT NATIONAL DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2005-08-18 | — | — | WO | disclosed |
| EP-1559712-A1 | A method for manufacturing optically active coumaryl amino acid salts and the coumaryl aminoacid salts thus obtained | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2005-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161807-A1 | Method for manufacturing optically pure coumaryl amino acids and the novel coumaryl aminoacids thus obtained | CRYAA, BCAT2, BCAT1 | KMT2A 3259/4885MEN1 4557/4885NOS3 1162/4885 |
| US-20110117556-A1 | HIGH-SENSITIVE FLUORESCENT ENERGY TRANSFER ASSAY USING FLUORESCENT AMINO ACIDS AND FLUORESENT PROTEINS | SLC7A1, SARS1, GFPT1 | KMT2A 3456/4885MEN1 3695/4885NOS3 3567/4885 |
| US-20150369800-A1 | HIGH-SENSITIVE FLUORESCENT ENERGY TRANSFER ASSAY USING FLUORESCENT AMINO ACIDS AND FLUORESENT PROTEINS | GFPT1, PHAX, TARBP1 | KMT2A 3484/4885MEN1 3636/4885NOS3 3611/4885 |
| US-20170370916-A1 | HIGH-SENSITIVE FLUORESCENT ENERGY TRANSFER ASSAY USING FLUORESCENT AMINO ACIDS AND FLUORESCENT PROTEINS | ACP1, BCAT1, SARS1 | KMT2A 3471/4885MEN1 3513/4885NOS3 3607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.