Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 4/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28880354 | 1.00 | SOS1 (0.34) | SOS1ALKLMNAALDH1A1TRPA1 | |
| SCHEMBL28880414 | 0.87 | TRPA1 (0.32) | SOS1ALKLMNAALDH1A1TRPA1 | |
| SCHEMBL28880416 | 0.87 | TRPA1 (0.32) | SOS1ALKLMNAALDH1A1TRPA1 | |
| SCHEMBL28880344 | 0.77 | L3MBTL1 (0.35) | SOS1LMNAALDH1A1 | |
| SCHEMBL28880345 | 0.77 | L3MBTL1 (0.35) | SOS1LMNAALDH1A1 | |
| SCHEMBL23526343 | 0.76 | SOS1 (0.36) | SOS1ALKCYP11B2 | |
| SCHEMBL29945876 | 0.76 | SOS1 (0.36) | SOS1ALKCYP11B2 | |
| SCHEMBL23526345 | 0.76 | SOS1 (0.36) | SOS1ALKCYP11B2 | |
| SCHEMBL25839061 | 0.75 | SOS1 (0.38) | SOS1ALKCYP11B2 | |
| SCHEMBL23526447 | 0.74 | SOS1 (0.41) | SOS1LMNATRPA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135315-A | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2022-09-30 | — | — | CN | disclosed |