Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.32 |
| ▸ | CHRNG | P07510 | 1/20 | 0.32 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CHRND | Q07001 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27796923 | 0.83 | NPC1 (0.36) | SLC6A3NPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL28880397 | 0.78 | NPC1 (0.35) | SLC6A3NPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL29164145 | 0.78 | NOTUM (0.36) | SLC6A3NPC1RAB9AALPLCHRNA1 | |
| SCHEMBL28698427 | 0.76 | SLC6A3 (0.44) | SLC6A3NPC1RAB9AAAK1ALPL | |
| SCHEMBL28977248 | 0.76 | AAK1 (0.45) | NPC1RAB9AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL27931108 | 0.76 | AAK1 (0.45) | NPC1RAB9AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL28880364 | 0.74 | TRPA1 (0.41) | AAK1MEN1KMT2A | |
| SCHEMBL29164033 | 0.74 | LMNA (0.32) | TACR1 | |
| SCHEMBL29945748 | 0.74 | TRPA1 (0.41) | AAK1MEN1KMT2A | |
| SCHEMBL26464327 | 0.74 | TRPA1 (0.41) | AAK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135315-A | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2022-09-30 | — | — | CN | disclosed |