Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2886631 | 0.70 | FFAR4 (0.46) | FFAR4FFAR1TRPV6CNR1CNR2 | |
| SCHEMBL2888042 | 0.66 | SLC6A4 (0.39) | LMNAKMT2A | |
| SCHEMBL28429634 | 0.65 | HTR7 (0.39) | LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL9016024 | 0.64 | ESR1 (0.46) | TRPV1ALDH1A1KDM4ELMNA | |
| SCHEMBL12377642 | 0.64 | TSHR (0.46) | ALDH1A1CNR1CNR2HTTKMT2A | |
| SCHEMBL15777915 | 0.63 | FFAR4 (0.47) | FFAR4FFAR1TRPV6ALDH1A1PKM | |
| SCHEMBL9016039 | 0.63 | ESR1 (0.48) | TRPV1ALDH1A1KDM4ELMNAHTT | |
| SCHEMBL11202793 | 0.63 | TSHR (0.37) | ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL74805 | 0.62 | TYR (0.42) | ALDH1A1CNR1CNR2KMT2A | |
| SCHEMBL73794 | 0.61 | CNR2 (0.44) | ALDH1A1CNR1CNR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700653-B2 | Halogen-substituted aminodicarboxylic acid derivatives | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-04-20 | — | — | US | disclosed |
| US-7067694-B2 | Halogen-substituted amino dicarboxylic acid derivatives as medicaments for treating cardiovascular diseases | BAYER AKTIENGESELLSCHAFT (DE) | 2006-06-27 | — | — | US | disclosed |
| US-20060111444-A1 | Novel halogen-substituted aminodicarboxylic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2006-05-25 | — | — | US | disclosed |
| US-20040092593-A1 | Halogen-substituted amino dicarboxylic acid derivatives as medicaments for treating cardiovascular diseases | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2004-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092593-A1 | Halogen-substituted amino dicarboxylic acid derivatives as medicaments for treating cardiovascular diseases | BCAT2, DDC, AADAT | FFAR4 321/4885FFAR1 199/4885SMPD1 4303/4885 |
| US-20060111444-A1 | Novel halogen-substituted aminodicarboxylic acid derivatives | FABP3, PPARD, FABP1 | FFAR4 45/4885FFAR1 53/4885SMPD1 2556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.