Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | TYR | P14679 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29089267 | 0.98 | SMN1; SMN2 (0.51) | SMN1; SMN2POLBHPGDTYRDAO | |
| SCHEMBL259563 | 0.76 | HPGD (0.55) | SMN1; SMN2POLBHPGDTYRDAO | |
| SCHEMBL3692740 | 0.73 | HPGD (0.51) | SMN1; SMN2POLBHPGDTYRDAO | |
| SCHEMBL145996 | 0.72 | SMN1; SMN2 (0.51) | SMN1; SMN2POLBHPGDTYRDAO | |
| SCHEMBL28026164 | 0.72 | MAPT (0.55) | SMN1; SMN2POLBHPGDCA12CA9 | |
| SCHEMBL169632 | 0.72 | HPGD (0.46) | SMN1; SMN2POLBHPGDTYRDAO | |
| SCHEMBL28682649 | 0.71 | MAOB (0.57) | SMN1; SMN2POLBHPGDTYRDAO | |
| SCHEMBL11881976 | 0.71 | MAOB (0.57) | SMN1; SMN2POLBHPGDTYRDAO | |
| SCHEMBL971515 | 0.70 | CYP2A6 (0.58) | SMN1; SMN2POLBHPGDTYRDAO | |
| SCHEMBL29494145 | 0.70 | CYP2A6 (0.58) | SMN1; SMN2POLBHPGDTYRDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116874457-A | Coumarin derivative containing acylhydrazone sulfoxide and synthetic method and application thereof | 中国热带农业科学院环境与植物保护研究所 | 2023-10-13 | — | — | CN | claimed |
| CN-116874457-A | Coumarin derivative containing acylhydrazone sulfoxide and synthetic method and application thereof | 中国热带农业科学院环境与植物保护研究所 | 2023-10-13 | — | — | CN | disclosed |
| CN-115322180-A | Coumarin pyrazolone fluorescent probe and preparation method and application thereof | 南京医科大学康达学院 | 2022-11-11 | — | — | CN | disclosed |