SCHEMBL169632

SCHEMBL169632

C=CCN(CC=C)c1cc2ccccc2oc1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
TYR P14679 1/20 0.46
DAO P14920 1/20 0.46
AKR1B1 P15121 1/20 0.46
POLB P06746 1/20 0.46
MAOB P27338 5/20 0.44
ALDH1A1 P00352 3/20 0.44
KDM4E B2RXH2 2/20 0.44
RAB9A P51151 2/20 0.44
CA12 O43570 3/20 0.43
CA9 Q16790 3/20 0.43
CA1 P00915 2/20 0.43
GPR35 Q9HC97 2/20 0.43
CA3 P07451 1/20 0.43
TSHR P16473 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
CA5A P35218 1/20 0.43
CA7 P43166 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL145996 0.80 SMN1; SMN2 (0.51) HPGDSMN1; SMN2TYRDAOAKR1B1
SCHEMBL30241252 0.75 MAOB (0.54) HPGDSMN1; SMN2TYRDAOAKR1B1
SCHEMBL28996736 0.75 MAOB (0.54) HPGDSMN1; SMN2TYRDAOAKR1B1
SCHEMBL259563 0.74 HPGD (0.55) HPGDSMN1; SMN2TYRDAOAKR1B1
SCHEMBL3267547 0.73 MAOA (0.54) HPGDSMN1; SMN2TYRDAOAKR1B1
SCHEMBL28880946 0.72 SMN1; SMN2 (0.53) HPGDSMN1; SMN2TYRDAOAKR1B1
SCHEMBL3692740 0.71 HPGD (0.51) HPGDSMN1; SMN2TYRDAOAKR1B1
SCHEMBL5960738 0.71 ALDH1A1 (0.42) HPGDSMN1; SMN2TYRDAOAKR1B1
SCHEMBL29089267 0.71 SMN1; SMN2 (0.51) HPGDSMN1; SMN2TYRDAOAKR1B1
Thiourea SCHEMBL6715523 0.71 SMN1; SMN2 (0.46) HPGDSMN1; SMN2TYRDAOAKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1781 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024011209-A2 ENGINEERED LIQUID CRYSTAL SHUTTER AS A DYNAMIC LONG-PASS OPTICAL FILTER Blaze Bioscience, Inc. (US) 2024-01-11 WO claimed
US-11746126-B2 Bicyclic peptide ligands with detectable moieties and uses thereof Bicyclerd Limited (GB) 2023-09-05 US claimed
US-11725222-B2 Cleavable nucleotide analogs and uses thereof PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-08-15 US claimed
US-20230149478-A1 COMPOSITIONS AND METHODS FOR DIABETES TREATMENT THE GENERAL HOSPITAL CORPORATION 2023-05-18 US claimed
EP-4172600-A1 SYSTEMS AND METHODS FOR SIMULTANEOUS NEAR-INFRARED LIGHT AND VISIBLE LIGHT IMAGING Blaze Bioscience, Inc. (US) 2023-05-03 EP claimed
CN-116034301-A System and method for simultaneous near infrared and visible imaging 光明之火生物科学公司 2023-04-28 CN claimed
EP-4125829-A2 COMPOSITIONS AND METHODS FOR DIABETES TREATMENT THE GENERAL HOSPITAL CORPORATION (US) 2023-02-08 EP claimed
WO-2021263159-A1 SYSTEMS AND METHODS FOR SIMULTANEOUS NEAR-INFRARED LIGHT AND VISIBLE LIGHT IMAGING Blaze Bioscience, Inc. (US) 2021-12-30 WO claimed
WO-2021195344-A2 COMPOSITIONS AND METHODS FOR DIABETES TREATMENT THE GENERAL HOSPITAL CORPORATION (US) 2021-09-30 WO claimed
WO-2021126341-A1 METHODS OF TREATING VASCULAR LESIONS AND MALFORMATIONS Blaze Bioscience, Inc. (US) 2021-06-24 WO claimed
WO-2002079387-A2 MODULAR MOLECULAR CLASPS AND USES THEREOF ENGENEOS, INC. (US) 2002-10-10 WO claimed
US-20020142336-A1 Methods for determining a nucleotide at a specific location within a nucleic acid molecule GENOME THERAPEUTICS CORPORATION (US) 2002-10-03 US claimed
WO-2002063049-A2 METHODS FOR DETERMINING A NUCLEOTIDE AT A SPECIFIC LOCATION WITHIN A NUCLEIC ACID MOLECULE GENOME THERAPEUTICS CORPORATION (US) 2002-08-15 WO claimed
EP-1133697-B1 METHOD FOR MODIFYING AND IDENTIFYING FUNCTIONAL SITES IN PROTEINS XERION PHARMACEUTICALS GMBH (DE) 2002-08-07 EP claimed
EP-1119315-A4 DELIVERY OF PHOSPHOINOSITIDE POLYPHOSPHATES INTO CELLS UNIV UTAH RES FOUND (US) 2002-04-17 EP claimed
US-6320041-B1 COMPOSITIONS COMPRISING ACTIVATED CARBOXYLIC ESTER MOIETY, ALKYL TETHER AND NUCLEIC ACID BINDING MOIETY TRILINK BIOTECHNOLOGIES, INC. 2001-11-20 US claimed
EP-1119315-A2 DELIVERY OF PHOSPHOINOSITIDE POLYPHOSPHATES INTO CELLS UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2001-08-01 EP claimed
WO-2000018949-A9 DELIVERY OF PHOSPHOINOSITIDE POLYPHOSPHATES INTO CELLS UNIV UTAH RES FOUND (US) 2000-08-31 WO claimed
WO-2000018949-A2 DELIVERY OF PHOSPHOINOSITIDE POLYPHOSPHATES INTO CELLS UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2000-04-06 WO claimed
US-5453517-A Covalently attached to fluorophores and/or polymers; detoxify excess metals, in vitro buffers, optical indicators of ionic transients MOLECULAR PROBES, INC. (US) 1995-09-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11746126-B2 Bicyclic peptide ligands with detectable moieties and uses thereof VIP, NGLY1, GRPR HPGD 3614/4885SMN1; SMN2 4492/4885TYR 2506/4885
US-20230149478-A1 COMPOSITIONS AND METHODS FOR DIABETES TREATMENT SLC2A1, G6PD, HK1 HPGD 586/4885SMN1; SMN2 1586/4885TYR 931/4885
US-11725222-B2 Cleavable nucleotide analogs and uses thereof TYMP, DUT, NT5C3B HPGD 432/4885SMN1; SMN2 2082/4885TYR 3712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.