SCHEMBL28883302

SCHEMBL28883302

COC(=O)[C@@H](Cc1ccc(OC)cc1)NC(=O)C(C)(C)C

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.56
MMP1 P03956 4/20 0.50
KMT2A Q03164 2/20 0.50
ALDH1A1 P00352 2/20 0.50
MEN1 O00255 1/20 0.50
LMNA P02545 1/20 0.50
LDHA P00338 1/20 0.50
MMP3 P08254 2/20 0.47
MMP9 P14780 1/20 0.47
GAA P10253 1/20 0.47
RAB9A P51151 1/20 0.47
ATM Q13315 2/20 0.47
TSHR P16473 1/20 0.46
MDM4 O15151 1/20 0.46
MDM2 Q00987 1/20 0.46
FPR2 P25090 1/20 0.46
THRB P10828 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
HSD17B10 Q99714 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7306740 0.89 FPR2 (0.59) NPSR1MMP1KMT2AALDH1A1LDHA
SCHEMBL30000376 0.89 FPR2 (0.59) NPSR1MMP1KMT2AALDH1A1LDHA
SCHEMBL7306758 0.89 FPR2 (0.59) NPSR1MMP1KMT2AALDH1A1LDHA
SCHEMBL12863003 0.87 MDM4 (0.60) NPSR1KMT2AALDH1A1ATMTSHR
SCHEMBL28883406 0.86 NOS2 (0.55) KMT2AALDH1A1MEN1LMNAATM
SCHEMBL28883318 0.86 NOS2 (0.61) KMT2AALDH1A1MEN1GAAATM
SCHEMBL6510996 0.86 LNPEP (0.49) NPSR1KMT2AALDH1A1MEN1LMNA
SCHEMBL12863012 0.85 ATM (0.63) KMT2AALDH1A1MEN1LMNAGAA
SCHEMBL11940456 0.85 ATM (0.63) KMT2AALDH1A1MEN1LMNAGAA
SCHEMBL20211752 0.85 ATM (0.63) KMT2AALDH1A1MEN1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115340468-A (R) -deuterated phenylalanine derivative and preparation method thereof 西南大学 2022-11-15 CN disclosed