Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 3/20 | 0.35 |
| ▸ | GABRD | O14764 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3716519 | 0.79 | G6PD (0.55) | CASP6CASP7G6PDALDH1A1KMT2A | |
| SCHEMBL1551335 | 0.73 | CASP7 (0.50) | CASP6CASP7G6PDCYP1A2ALDH1A1 | |
| SCHEMBL29792992 | 0.72 | CASP7 (0.58) | CASP6CASP7G6PDCYP1A2ALDH1A1 | |
| SCHEMBL690406 | 0.72 | CASP7 (0.58) | CASP6CASP7G6PDCYP1A2ALDH1A1 | |
| SCHEMBL574774 | 0.72 | CA12 (0.37) | CASP6CASP7G6PDALDH1A1KMT2A | |
| SCHEMBL8442035 | 0.69 | HMGB1 (0.41) | CYP1A2ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL29482064 | 0.69 | ALDH1A1 (0.46) | CASP6CASP7ALDH1A1KMT2AMAPT | |
| SCHEMBL179933 | 0.69 | ALDH1A1 (0.46) | CASP6CASP7ALDH1A1KMT2AMAPT | |
| SCHEMBL31494238 | 0.67 | GABRP (0.50) | CASP6CASP7G6PDCYP1A2ALDH1A1 | |
| SCHEMBL2921220 | 0.67 | GABRP (0.50) | CASP6CASP7G6PDCYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115181164-A | Derivatives of amatoxins and their coupling to cell binding molecules | 杭州多禧生物科技有限公司 | 2022-10-14 | — | — | CN | disclosed |