Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.34 |
| ▸ | KDM4A | O75164 | 2/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.34 |
| ▸ | TET3 | O43151 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | PPM1B | O75688 | 1/20 | 0.33 |
| ▸ | GRM8 | O00222 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GSR | P00390 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27909276 | 0.83 | LMNA (0.51) | MEN1HTTKMT2ALMNASLC6A3 | |
| SCHEMBL10888326 | 0.78 | GPR84 (0.41) | MEN1HTTKMT2ASLC6A3 | |
| SCHEMBL9042034 | 0.78 | MEN1 (0.40) | MEN1HTTKMT2ALMNASLC6A3 | |
| SCHEMBL12497665 | 0.75 | MEN1 (0.54) | MEN1HTTKMT2ALMNASLC6A3 | |
| SCHEMBL2481407 | 0.74 | KMT2A (0.49) | MEN1HTTKMT2ALMNASLC6A3 | |
| SCHEMBL2481406 | 0.74 | KMT2A (0.49) | MEN1HTTKMT2ALMNASLC6A3 | |
| SCHEMBL2481404 | 0.74 | KMT2A (0.49) | MEN1HTTKMT2ALMNASLC6A3 | |
| SCHEMBL28572076 | 0.73 | ALDH1A1 (0.44) | LMNAALDH1A1TET2KDM4AKDM4C | |
| SCHEMBL10874251 | 0.73 | SLC6A3 (0.42) | MEN1HTTKMT2ALMNASLC6A3 | |
| SCHEMBL24293555 | 0.70 | TET2 (0.44) | TET2KDM4AKDM4CKDM2ATET3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106999537-B | Novel α 4 β 7 peptide monomer and dimer antagonists | 领导医疗有限公司 | 2020-01-31 | — | — | CN | disclosed |