Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28889180 | 0.85 | ALDH1A1 (0.51) | ALDH1A1GAA | |
| SCHEMBL28889282 | 0.80 | ALDH1A1 (0.40) | ALDH1A1GAAMEN1GFERKMT2A | |
| SCHEMBL28889317 | 0.78 | ALDH1A1 (0.40) | ALDH1A1GAAMEN1GFERKMT2A | |
| SCHEMBL28889263 | 0.73 | HDAC4 (0.41) | GAA | |
| SCHEMBL2280708 | 0.70 | ALDH1A1 (0.41) | ALDH1A1GAAMEN1GFERKMT2A | |
| SCHEMBL28889345 | 0.69 | ADRB2 (0.37) | ALDH1A1GAAMEN1GFERKMT2A | |
| SCHEMBL28889190 | 0.68 | ADRB2 (0.40) | ALDH1A1GAA | |
| SCHEMBL1507854 | 0.67 | ALDH1A1 (0.53) | ALDH1A1GAAMEN1GFERKMT2A | |
| SCHEMBL17897224 | 0.66 | RXRA (0.36) | — | |
| SCHEMBL5439970 | 0.65 | MEN1 (0.40) | ALDH1A1GAAMEN1GFERKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022222911-A1 | PYRIMIDONE COMPOUND AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-10-27 | — | — | WO | disclosed |
| CN-115215862-A | Pyrimidone compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-21 | — | — | CN | disclosed |