Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.34 |
| ▸ | CTSA | P10619 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29941884 | 0.89 | SMARCA2 (0.38) | LMNASMARCA2CTSAL3MBTL1LIMK1 | |
| SCHEMBL28889168 | 0.86 | CTSA (0.43) | ALDH1A1MEN1KMT2AHTTLMNA | |
| SCHEMBL29941823 | 0.84 | ADRB2 (0.40) | ALDH1A1MEN1KMT2AHTTLMNA | |
| SCHEMBL28889244 | 0.82 | IDO1 (0.35) | ALDH1A1MEN1KMT2AHTTLMNA | |
| SCHEMBL28889260 | 0.79 | SMARCA2 (0.38) | SMARCA2CTSASMN1; SMN2 | |
| SCHEMBL29893979 | 0.78 | ADRB2 (0.38) | ALDH1A1MEN1KMT2AHTTLMNA | |
| SCHEMBL28889337 | 0.78 | MEN1 (0.39) | ALDH1A1MEN1KMT2AHTTLMNA | |
| SCHEMBL28889346 | 0.76 | CTSA (0.42) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL29942331 | 0.75 | ADRB2 (0.38) | ALDH1A1KMT2AHTTLMNAMAPT | |
| SCHEMBL28889189 | 0.75 | CTSA (0.45) | ALDH1A1MEN1KMT2AMAPTCTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215862-A | Pyrimidone compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-21 | — | — | CN | disclosed |