Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28889204 | 0.87 | ADRB2 (0.39) | KMT2AADRB2EPAS1MAPTNPSR1 | |
| SCHEMBL28959207 | 0.85 | KMT2A (0.40) | KMT2AADRB2EPAS1MAPTNPSR1 | |
| SCHEMBL29893753 | 0.83 | ADRB2 (0.37) | KMT2AADRB2LMNAPOLBMEN1 | |
| SCHEMBL28889284 | 0.83 | ADRB2 (0.37) | KMT2AADRB2LMNAPOLBMEN1 | |
| SCHEMBL28959159 | 0.80 | ADRB2 (0.38) | KMT2AADRB2EPAS1MAPTNPSR1 | |
| SCHEMBL28889336 | 0.80 | HDAC4 (0.41) | ADRB2LMNAPOLBL3MBTL1P2RY1 | |
| SCHEMBL28889308 | 0.80 | ADRB2 (0.38) | KMT2AADRB2EPAS1MAPTLMNA | |
| SCHEMBL28889237 | 0.80 | ADRB2 (0.39) | ADRB2MAPTKDM4EL3MBTL1P2RY1 | |
| SCHEMBL29893638 | 0.79 | MEN1 (0.39) | KMT2AADRB2EPAS1MAPTNPSR1 | |
| SCHEMBL28889288 | 0.79 | MEN1 (0.39) | KMT2AADRB2EPAS1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215862-A | Pyrimidone compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-21 | — | — | CN | disclosed |