Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1763583 | 0.86 | LMNA (0.47) | ALDH1A1RAB9ANPC1HSD17B10NPSR1 | |
| SCHEMBL1763578 | 0.86 | LMNA (0.47) | ALDH1A1RAB9ANPC1HSD17B10NPSR1 | |
| SCHEMBL29816602 | 0.85 | NPC1 (0.50) | ALDH1A1RAB9ANPC1HSD17B10GAA | |
| SCHEMBL26502783 | 0.82 | SPHK1 (0.43) | ALDH1A1RAB9ANPC1HSD17B10GAA | |
| SCHEMBL10118460 | 0.78 | L3MBTL1 (0.46) | ALDH1A1RAB9ANPC1TSHRKDM4E | |
| SCHEMBL9068282 | 0.77 | ALDH1A1 (0.48) | ALDH1A1RAB9AGAATSHRKDM4E | |
| SCHEMBL9068477 | 0.77 | ALDH1A1 (0.48) | ALDH1A1RAB9AGAATSHRKDM4E | |
| SCHEMBL17394233 | 0.75 | FPR3 (0.49) | RAB9ANPC1NPSR1LMNAKMT2A | |
| SCHEMBL17394232 | 0.75 | FPR3 (0.49) | RAB9ANPC1NPSR1LMNAKMT2A | |
| SCHEMBL17928085 | 0.74 | LMNA (0.47) | ALDH1A1RAB9ANPC1HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111164072-A | β -hydroxy heterocyclic amines and their use in the treatment of hyperglycaemia | 阿托基公司 | 2020-05-15 | — | — | CN | disclosed |