Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9068282 | 1.00 | ALDH1A1 (0.48) | ALDH1A1GAATSHRKDM4EKMT2A | |
| SCHEMBL9068328 | 0.94 | ALDH1A1 (0.46) | ALDH1A1GAATSHRKDM4EKMT2A | |
| SCHEMBL7477251 | 0.89 | FKBP1A (0.42) | ALDH1A1GAATSHRKDM4ELMNA | |
| SCHEMBL29285446 | 0.87 | LMNA (0.45) | KMT2ALMNANPSR1L3MBTL1MEN1 | |
| SCHEMBL27031270 | 0.86 | ALDH1A1 (0.44) | ALDH1A1POLBRAB9ACYP2D6CASP3 | |
| SCHEMBL7485723 | 0.86 | FKBP1A (0.40) | ALDH1A1GAATSHRKDM4ENPSR1 | |
| SCHEMBL8702996 | 0.85 | LMNA (0.44) | ALDH1A1KMT2ALMNANPSR1L3MBTL1 | |
| SCHEMBL18497662 | 0.84 | LMNA (0.44) | ALDH1A1GAATSHRKDM4EKMT2A | |
| SCHEMBL16538625 | 0.82 | GPR119 (0.45) | KMT2ALMNANPSR1L3MBTL1CASP3 | |
| SCHEMBL16538611 | 0.82 | GPR119 (0.45) | KMT2ALMNANPSR1L3MBTL1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556864-A | TREATMENT OF CIRCULATORY DISEASES AND PSYCHOSIS | SANKYO COMPANY, LIMITED (JP) | 1996-09-17 | — | — | US | disclosed |