Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.44 |
| ▸ | MAP2K6 | P52564 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.44 |
| ▸ | NEK10 | Q6ZWH5 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1840712 | 0.94 | ALDH1A1 (0.49) | ALDH1A1TSHRKDM4EHTTPDE10A | |
| SCHEMBL28279288 | 0.74 | MAP2K3 (0.53) | ALDH1A1KDM4EHTTLCKMAP2K3 | |
| SCHEMBL28844539 | 0.74 | SIRT3 (0.46) | ALDH1A1KDM4EHTTLCKMAP2K3 | |
| SCHEMBL26606768 | 0.74 | THRB (0.43) | KDM4EHPGDGRM2 | |
| SCHEMBL30471260 | 0.73 | LCK (0.67) | ALDH1A1TSHRKDM4EHTTPDE10A | |
| SCHEMBL28158782 | 0.73 | LCK (0.49) | ALDH1A1TSHRHTTPDE10ALCK | |
| SCHEMBL14883918 | 0.72 | HTT (0.69) | ALDH1A1TSHRKDM4EHTTPDE10A | |
| SCHEMBL2017393 | 0.71 | LMNA (0.47) | ALDH1A1KDM4EHTTPDE10ALCK | |
| SCHEMBL1332157 | 0.71 | MAP2K3 (0.50) | ALDH1A1KDM4EPDE10ALCKMAP2K3 | |
| SCHEMBL28386669 | 0.71 | ELANE (0.42) | MEN1KMT2ADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115197154-A | HPK1 inhibitor and application thereof in medicine | 贝达药业股份有限公司 | 2022-10-18 | — | — | CN | disclosed |