Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EML4 | Q9HC35 | 15/20 | 0.47 |
| ▸ | ALK | Q9UM73 | 15/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 10/20 | 0.44 |
| ▸ | ROS1 | P08922 | 10/20 | 0.44 |
| ▸ | FLT3 | P36888 | 10/20 | 0.44 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29876463 | 1.00 | EML4 (0.47) | EML4ALKPIK3CDRETROS1 | |
| SCHEMBL28891616 | 0.85 | ADRA2A (0.41) | EML4ALKROS1FLT3PIM1 | |
| SCHEMBL29875779 | 0.85 | ADRA2A (0.41) | EML4ALKROS1FLT3PIM1 | |
| SCHEMBL29875589 | 0.83 | RET (0.58) | EML4ALKRETROS1FLT3 | |
| SCHEMBL28891673 | 0.83 | RET (0.58) | EML4ALKRETROS1FLT3 | |
| SCHEMBL13405476 | 0.78 | PIM1 (0.51) | ALKPIK3CDRETROS1PIM1 | |
| SCHEMBL29875994 | 0.77 | KDM4E (0.41) | EML4ALKRETROS1FLT3 | |
| SCHEMBL28891734 | 0.77 | KDM4E (0.41) | EML4ALKRETROS1FLT3 | |
| SCHEMBL28891635 | 0.76 | SLC2A1 (0.41) | EML4ALKRETROS1FLT3 | |
| SCHEMBL28891628 | 0.76 | SLC2A1 (0.41) | EML4ALKROS1FLT3PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115197154-A | HPK1 inhibitor and application thereof in medicine | 贝达药业股份有限公司 | 2022-10-18 | — | — | CN | disclosed |