Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.39 |
| ▸ | TTK | P33981 | 2/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 4/20 | 0.37 |
| ▸ | SRC | P12931 | 3/20 | 0.37 |
| ▸ | EML4 | Q9HC35 | 2/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.37 |
| ▸ | PLK1 | P53350 | 2/20 | 0.37 |
| ▸ | PLK4 | O00444 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | ROS1 | P08922 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
| ▸ | MARK3 | P27448 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28891635 | 0.92 | SLC2A1 (0.41) | SLC2A1PIM1TTKPIM2CDK2 | |
| SCHEMBL28891616 | 0.87 | ADRA2A (0.41) | SLC2A1PIM1TTKPIM2CDK2 | |
| SCHEMBL29875779 | 0.87 | ADRA2A (0.41) | SLC2A1PIM1TTKPIM2CDK2 | |
| SCHEMBL28891651 | 0.86 | SLC2A1 (0.54) | SLC2A1PIM1TTKPIM2CDK2 | |
| SCHEMBL29875994 | 0.85 | KDM4E (0.41) | SLC2A1PIM1TTKPIM2EML4 | |
| SCHEMBL28891734 | 0.85 | KDM4E (0.41) | SLC2A1PIM1TTKPIM2EML4 | |
| SCHEMBL28891739 | 0.82 | SLC2A1 (0.39) | SLC2A1CDK2EML4ALKAURKA | |
| SCHEMBL29875822 | 0.77 | KDM4E (0.38) | EML4ALKCHEK1CLK4LRRK2 | |
| SCHEMBL29876463 | 0.76 | EML4 (0.47) | PIM1EML4ALKROS1FLT3 | |
| SCHEMBL28891852 | 0.76 | EML4 (0.47) | PIM1EML4ALKROS1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115197154-A | HPK1 inhibitor and application thereof in medicine | 贝达药业股份有限公司 | 2022-10-18 | — | — | CN | disclosed |