Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30002055 | 1.00 | SCN1A (0.46) | SCN1ASCN5ASCN8APTGESLMNA | |
| SCHEMBL28892812 | 0.86 | CHEK1 (0.41) | LMNACASP3SENP8SENP7SENP6 | |
| SCHEMBL28959518 | 0.85 | LMNA (0.42) | PTGESLMNACASP3SENP8SENP7 | |
| SCHEMBL28892628 | 0.85 | GAA (0.40) | PTGESLMNACASP3SENP8SENP7 | |
| SCHEMBL30003246 | 0.85 | GAA (0.40) | PTGESLMNACASP3SENP8SENP7 | |
| SCHEMBL28892367 | 0.83 | KMT2A (0.41) | SCN1ASCN5ASCN8ALMNACASP3 | |
| SCHEMBL30003178 | 0.83 | LMNA (0.42) | PTGESLMNACASP3SENP8SENP7 | |
| SCHEMBL30001950 | 0.82 | ALDH1A1 (0.52) | PTGESLMNAGAAPKMMAPT | |
| SCHEMBL28892526 | 0.82 | SCN1A (0.47) | SCN1ASCN5ASCN8AGAAMAPT | |
| SCHEMBL30002548 | 0.82 | SCN1A (0.47) | SCN1ASCN5ASCN8AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |