Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28892526 | 1.00 | SCN1A (0.47) | SCN1ASCN5ASCN8AADORA2AMAPT | |
| SCHEMBL28892213 | 0.84 | KIT (0.37) | SCN1ASCN5ASCN8AMAPTGAA | |
| SCHEMBL30002637 | 0.84 | KIT (0.37) | SCN1ASCN5ASCN8AMAPTGAA | |
| SCHEMBL30002926 | 0.83 | KIT (0.41) | — | |
| SCHEMBL28892234 | 0.83 | MAOA (0.39) | MAPTGAASMN1; SMN2TDP1PDE10A | |
| SCHEMBL30002556 | 0.83 | MAOA (0.39) | MAPTGAASMN1; SMN2TDP1PDE10A | |
| SCHEMBL30002055 | 0.82 | SCN1A (0.46) | SCN1ASCN5ASCN8AADORA2AMAPT | |
| SCHEMBL28893045 | 0.82 | SCN1A (0.46) | SCN1ASCN5ASCN8AADORA2AMAPT | |
| SCHEMBL30002665 | 0.81 | SCN1A (0.37) | SCN1ASCN5ASCN8AMAPTGAA | |
| SCHEMBL28892667 | 0.81 | SCN1A (0.37) | SCN1ASCN5ASCN8AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |