SCHEMBL28894372

SCHEMBL28894372

C=CC(=O)OC(CCCCC)[Si](OCC)(OCC)OCC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.41
HPGD P15428 1/20 0.41
THRB P10828 2/20 0.36
THRA P10827 1/20 0.33
ZDHHC20 Q5W0Z9 2/20 0.33
ZDHHC2 Q9UIJ5 2/20 0.33
ZDHHC7 Q9NXF8 1/20 0.32
GPR84 Q9NQS5 3/20 0.32
FFAR1 O14842 1/20 0.32
CA1 P00915 1/20 0.32
ABCB1 P08183 1/20 0.31
FAAH O00519 1/20 0.31
TP53 P04637 2/20 0.31
MAPT P10636 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HIF1A Q16665 1/20 0.31
LCK P06239 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4202060 0.98 TSHR (0.40) TSHRHPGDTHRBTHRAZDHHC20
SCHEMBL21224467 0.98 TSHR (0.40) TSHRHPGDTHRBTHRAZDHHC20
SCHEMBL29005322 0.98 TSHR (0.40) TSHRHPGDTHRBTHRAZDHHC20
SCHEMBL20336764 0.98 TSHR (0.40) TSHRHPGDTHRBTHRAZDHHC20
SCHEMBL16536827 0.95 TSHR (0.45) TSHRHPGDTHRBTHRAZDHHC20
SCHEMBL1680181 0.89 TSHR (0.37) TSHRHPGDTHRBTP53ALDH1A1
SCHEMBL28471218 0.88 TSHR (0.46) TSHRHPGDTHRBTHRAZDHHC20
SCHEMBL9947807 0.86 TSHR (0.42) TSHRHPGDTHRBTHRAZDHHC20
SCHEMBL20336761 0.85 TSHR (0.41) TSHRHPGDTHRBTHRAZDHHC20
SCHEMBL28894199 0.85 TSHR (0.41) TSHRHPGDTHRBTHRAZDHHC20

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4563609-A1 PHOTOCURABLE COMPOSITION, CURED PRODUCT OF SAME, AND COATED ARTICLE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-06-04 EP disclosed
US-12194114-B2 Dental glass ionomer cement composition suitable for mechanical mixing KABUSHIKI KAISHA SHOFU (JP) 2025-01-14 US disclosed
US-20240315929-A1 DENTAL ADHESIVE KIT KURARAY NORITAKE DENTAL INC. (JP) 2024-09-26 US disclosed
US-20240174780-A1 HOLLOW PARTICLES AND USE THEREOF SEKISUI KASEI CO., LTD. (JP) 2024-05-30 US disclosed
EP-4360609-A1 DENTAL ADHESIVE KIT Kuraray Noritake Dental Inc. (JP) 2024-05-01 EP disclosed
WO-2024024370-A1 PHOTOCURABLE COMPOSITION, CURED PRODUCT OF SAME, AND COATED ARTICLE 信越化学工業株式会社 2024-02-01 WO disclosed
US-11883790-B2 Hollow particles, method for producing same, and usage of same SEKISUI KASEI CO., LTD. (JP) 2024-01-30 US disclosed
US-20240018358-A1 POLYSILOXANE-BASED RESIN AND UTILIZATION THEREOF KANEKA CORPORATION (JP) 2024-01-18 US disclosed
US-20230303404-A1 NANOPARTICLES, DISPERSION OF NANOPARTICLES, AND PRODUCTION METHOD OF NANOPARTICLES TOKYO OHKA KOGYO CO., LTD. (JP) 2023-09-28 US disclosed
US-20230279272-A1 AGROCHEMICAL-CONTAINING PRESSURE-SENSITIVE ADHESIVE TAPE NICHIBAN CO., LTD. (JP) 2023-09-07 US disclosed
WO-2022202269-A1 POLYSILOXANE-BASED RESIN AND UTILIZATION THEREOF 株式会社カネカ 2022-09-29 WO disclosed
WO-2022202173-A1 CURABLE RESIN COMPOSITION AND USE THEREOF 株式会社カネカ 2022-09-29 WO disclosed
WO-2022202784-A1 HOLLOW PARTICLES AND USE THEREOF 積水化成品工業株式会社 2022-09-29 WO disclosed
US-20220288550-A1 HOLLOW PARTICLES AND USE THEREOF SEKISUI PLASTICS CO., LTD. (JP) 2022-09-15 US disclosed
CN-115003759-A Resin composition, method for producing same, and multi-component curable resin composition 株式会社钟化 2022-09-02 CN disclosed
US-11369935-B2 Hollow particles and use thereof SEKISUI PLASTICS CO., LTD. (JP) 2022-06-28 US disclosed
CN-110651336-B Conductive paste composition, electrode device comprising same, and method for producing conductive paste composition 株式会社钟化 2022-05-17 CN disclosed
US-20220142875-A1 DENTAL GLASS IONOMER CEMENT COMPOSITION SUITABLE FOR MECHANICAL KNEADING KABUSHIKI KAISHA SHOFU (JP) 2022-05-12 US disclosed
EP-3995125-A1 DENTAL GLASS IONOMER CEMENT COMPOSITION SUITABLE FOR MECHANICAL MIXING Kabushiki Kaisha Shofu (JP) 2022-05-11 EP disclosed
WO-2022050170-A1 COMPOUND MATERIAL, MOLDED BODY, AND CURED PRODUCT OF COMPOUND MATERIAL 昭和電工マテリアルズ株式会社 2022-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240315929-A1 DENTAL ADHESIVE KIT ITGA1, CAD, ITGA2 TSHR 4522/4885HPGD 1722/4885THRB 3460/4885
US-20230303404-A1 NANOPARTICLES, DISPERSION OF NANOPARTICLES, AND PRODUCTION METHOD OF NANOPARTICLES CD63, NIBAN2, ZRANB2 TSHR 1000/4885HPGD 2412/4885THRB 3707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.