Trolamine

Trolamine

SCHEMBL2889481

CCC(C)(N)O.OCCN(CCO)CCO

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.34
MAPK1 P28482 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
HIF1A Q16665 1/20 0.34
HSD17B10 Q99714 1/20 0.34
MAPT P10636 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ARG1 P05089 1/20 0.33
ARG2 P78540 1/20 0.33
SLC29A1 Q99808 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trolamine SCHEMBL28164611 0.84 MAPT (0.36) HPGDMAPK1CYP1A2CYP2C9HIF1A
SCHEMBL21618434 0.80 MAPT (0.33) HPGDMAPK1CYP1A2CYP2C9HIF1A
Trolamine SCHEMBL4518758 0.79 MAPT (0.36) HPGDMAPK1CYP1A2CYP2C9HIF1A
SCHEMBL15651255 0.78 TSHR (0.43) CYP1A2ALDH1A1
SCHEMBL50175 0.78
SCHEMBL2889072 0.78
Trolamine SCHEMBL7754018 0.77 MAPT (0.35) HPGDMAPK1CYP1A2CYP2C9HIF1A
Trolamine SCHEMBL28825126 0.76 ARG1 (0.34) HPGDMAPK1CYP1A2CYP2C9HIF1A
Monoethanolamine SCHEMBL3844046 0.76 TSHR (0.47) ALDH1A1
SCHEMBL5965815 0.75 ARG1 (0.36) HPGDMAPK1CYP1A2CYP2C9HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1051460-B1 CONSTANT HEATING VALUE AQUEOUS FUEL MIXTURE AND METHOD FOR FORMULATING THE SAME TALISMAN CAPITAL TALON FUND LT (US) 2010-07-21 EP disclosed
US-7645305-B1 High stability fuel compositions CLEAN FUELS TECHNOLOGY, INC. (US) 2010-01-12 US disclosed
US-7491247-B1 Fuel emulsion compositions having reduced NOx emissions TALISMAN CAPITAL TALON FUND, LTD. 2009-02-17 US disclosed
US-7407522-B2 Stabile invert fuel emulsion compositions and method of making CLEAN FUELS TECHNOLOGY, INC. (US) 2008-08-05 US disclosed
US-20040255509-A1 Stabile invert fuel emulsion compositions and method of making CLEAN FUELS TECHNOLOGY, INC. 2004-12-23 US disclosed
US-6786938-B1 DIESEL FUEL, PURIFIED WATER, METHANOL, AMINO METHYL PROPANOL, 2-ETHYLHEXYL NITRATE AND NONIONIC SURFACTANT; INTERNAL COMBUSTION ENGINES CLEAN FUEL TECHNOLOGY, INC. 2004-09-07 US disclosed
EP-1051460-A4 CONSTANT HEATING VALUE AQUEOUS FUEL MIXTURE AND METHOD FOR FORMULATING THE SAME CLEAN FUELS TECHNOLOGY INC (US) 2004-04-28 EP disclosed
US-6656236-B1 Hydrocarbon petroleum distillate, purified water; alcohol antifreeze CLEAN FUEL TECHNOLOGY, INC. 2003-12-02 US disclosed
US-6607566-B1 Blending additive flow with hydrocarbon petroleum distillate flow in in-line blending station, blending mixture with flow of purified water in second in-line blending station, aging in reservoir, passing through shear pump to form fuel emulsion CLEAN FUEL TECHNOLOGY, INC. 2003-08-19 US disclosed
EP-1051460-A1 CONSTANT HEATING VALUE AQUEOUS FUEL MIXTURE AND METHOD FOR FORMULATING THE SAME CATERPILLAR INC. (US) 2000-11-15 EP disclosed
WO-1999063024-A1 STABILE INVERT FUEL EMULSION COMPOSITIONS AND METHOD OF MAKING CLEAN FUELS TECHNOLOGY, INC. (US) 1999-12-09 WO disclosed
WO-1999063025-A1 STABILE FUEL EMULSIONS AND METHOD OF MAKING CLEAN FUELS TECHNOLOGY, INC. (US) 1999-12-09 WO disclosed
WO-1999063026-A1 HIGH STABILITY FUEL COMPOSITIONS CLEAN FUELS TECHNOLOGY, INC. (US) 1999-12-09 WO disclosed
WO-1999031203-A1 CONSTANT HEATING VALUE AQUEOUS FUEL MIXTURE AND METHOD FOR FORMULATING THE SAME CATERPILLAR INC. (US) 1999-06-24 WO disclosed