Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 3/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL374482 | 0.95 | MIF (0.36) | CYP4F2CYP4A11MIFSMN1; SMN2ALDH1A1 | |
| Styrene SCHEMBL6703589 | 0.84 | ALDH1A1 (0.35) | SMN1; SMN2ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL157638 | 0.79 | MEP1B (0.34) | CYP4F2CYP4A11MRGPRX4MIFSMN1; SMN2 | |
| Methane SCHEMBL8750934 | 0.79 | MIF (0.41) | CYP4F2CYP4A11MIFALDH1A1KMT2A | |
| SCHEMBL5802770 | 0.78 | CYP4F2 (0.40) | CYP4F2CYP4A11MIFKMT2AMAPT | |
| Acetone SCHEMBL28493231 | 0.77 | NOS2 (0.43) | MIFSMN1; SMN2ALDH1A1NOS1NOS3 | |
| SCHEMBL5803944 | 0.77 | CYP4F2 (0.42) | CYP4F2CYP4A11MIFKMT2AMAPT | |
| SCHEMBL8856804 | 0.77 | NOS2 (0.38) | MIFSMN1; SMN2ALDH1A1NOS1NOS3 | |
| SCHEMBL3674472 | 0.77 | PTGS1 (0.37) | CYP4F2CYP4A11MRGPRX4MIFSMN1; SMN2 | |
| SCHEMBL30885594 | 0.76 | FOLH1 (0.56) | MRGPRX4SMN1; SMN2KMT2AMEP1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111356434-A | Composition comprising an oil and a polyionic complex comprising a cellulose-based cationic polymer having at least one fatty chain | 莱雅公司 | 2020-06-30 | — | — | CN | disclosed |