Styrene

Styrene

SCHEMBL6703589

C=C(C)c1cccc(CN=C=O)c1.C=Cc1ccccc1

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
MAPT P10636 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TP53 P04637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
BCHE P06276 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HDAC2 Q92769 1/20 0.32
MTNR1A P48039 2/20 0.32
MTNR1B P49286 2/20 0.32
GRIN2B Q13224 2/20 0.32
PTPN1 P18031 1/20 0.32
G6PC1 P35575 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL374482 0.88 MIF (0.36) ALDH1A1MEN1KMT2AMAPTNPSR1
Alcohol SCHEMBL28895010 0.84 CYP4F2 (0.37) ALDH1A1MEN1KMT2AMAPTNPSR1
Styrene SCHEMBL8724549 0.81 ALDH1A1 (0.50) ALDH1A1TSHRMEN1KMT2ATP53
SCHEMBL3628956 0.79 TP53 (0.44) ALDH1A1TSHRMEN1KMT2ATP53
Styrene SCHEMBL1171199 0.78 ALDH1A1 (0.54) ALDH1A1TSHRTP53TDP1CYP1A2
Styrene SCHEMBL6536677 0.74 CYP1A2 (0.42) ALDH1A1TSHRMEN1KMT2AMAPT
SCHEMBL30885594 0.73 FOLH1 (0.56) KMT2ACYP2D6CYP2C9SMN1; SMN2
SCHEMBL157638 0.73 MEP1B (0.34) ALDH1A1MEN1KMT2AMAPTSMN1; SMN2
Methane SCHEMBL8750934 0.73 MIF (0.41) ALDH1A1MEN1KMT2AMAPTNPSR1
Styrene SCHEMBL315930 0.72 ALDH1A1 (0.61) ALDH1A1TSHRMAPTTP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040076623-A1 Activated modular grafted polymeric surfaces MIMOTOPES PTY LTD (AU) 2004-04-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040076623-A1 Activated modular grafted polymeric surfaces SIGLEC7, PHAX, STUB1 ALDH1A1 4137/4885TSHR 2607/4885MEN1 4762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.