SCHEMBL374482

SCHEMBL374482

C=C(C)c1cccc(CN=C=O)c1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MIF P14174 2/20 0.36
ALDH1A1 P00352 4/20 0.35
NOS1 P29475 3/20 0.35
NOS3 P29474 2/20 0.35
NOS2 P35228 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
CYP3A4 P08684 1/20 0.35
NFKB1 P19838 1/20 0.35
KMT2A Q03164 3/20 0.34
MAPT P10636 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 2/20 0.34
FOLH1 Q04609 1/20 0.34
LOXL2 Q9Y4K0 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
CYP4F2 P78329 2/20 0.33
CYP4A11 Q02928 2/20 0.33
GRIN2B Q13224 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alcohol SCHEMBL28895010 0.95 CYP4F2 (0.37) MIFALDH1A1NOS1NOS3NOS2
Styrene SCHEMBL6703589 0.88 ALDH1A1 (0.35) ALDH1A1SMN1; SMN2KMT2AMAPTMEN1
Methane SCHEMBL8750934 0.83 MIF (0.41) MIFALDH1A1KMT2AMAPTKDM4E
SCHEMBL157638 0.83 MEP1B (0.34) MIFALDH1A1NOS1SMN1; SMN2KMT2A
SCHEMBL5802770 0.82 CYP4F2 (0.40) MIFKMT2AMAPTMEN1NPSR1
Acetone SCHEMBL28493231 0.81 NOS2 (0.43) MIFALDH1A1NOS1NOS3NOS2
SCHEMBL5803944 0.81 CYP4F2 (0.42) MIFKMT2AMAPTMEN1NPSR1
SCHEMBL8856804 0.81 NOS2 (0.38) MIFALDH1A1NOS1NOS3NOS2
SCHEMBL30885594 0.80 FOLH1 (0.56) SMN1; SMN2KMT2AFOLH1
SCHEMBL27661227 0.80 FOLH1 (0.56) SMN1; SMN2KMT2AFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1419763-B1 Cosmetic composition comprising tensioning latex and an amphiphilic ionic polymer OREAL (FR) 2006-07-26 EP claimed
EP-1255761-B1 SILICON CONTAINING COMPOUNDS FROM MICHAEL - TYPE ADDITION REACTIONS USEFUL AS MONOMERS AND MACROMERS BIOCOMPATIBLES UK LTD (GB) 2005-08-31 EP claimed
EP-1419763-A1 Cosmetic composition comprising tensioning latex and an amphiphilic ionic polymer L'OREAL (FR) 2004-05-19 EP claimed
WO-1998013398-A1 REACTIVE POLYMER PROCESSING UNIVERSITY OF BRADFORD (GB) 1998-04-02 WO claimed
JP-7247337-A None JP disclosed
US-12109280-B2 Oil-in-water emulsion comprising an amphiphilic polymer L'OREAL (FR) 2024-10-08 US disclosed
CN-112063130-B 3D printing copolyester and preparation method thereof 中瀚新材料科技有限公司 2023-03-31 CN disclosed
WO-2022102453-A1 TIRE 住友ゴム工業株式会社 2022-05-19 WO disclosed
US-11273112-B2 Process for treating keratin fibers using a halochromic triarylmethane direct dye, an alkaline revealer and then an acidic eraser L'OREAL (FR) 2022-03-15 US disclosed
US-20210186829-A1 OIL-IN-WATER EMULSION COMPRISING AN AMPHIPHILIC POLYMER L'OREAL (FR) 2021-06-24 US disclosed
US-10925815-B2 Oil-in-water emulsion comprising an amphiphilic polymer L'OREAL (FR) 2021-02-23 US disclosed
CN-112063130-A 3D printing copolyester and preparation method thereof 中瀚新材料科技有限公司 2020-12-11 CN disclosed
EP-0850259-A1 RETROREFLECTIVE ARTICLE CONTAINING A POLYESTER POLYURETHANE BINDER LAYER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-07-01 EP disclosed
WO-1997012284-A1 LIQUID INKS USING A CONTROLLED CRYSTALLINITY ORGANOSOL MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-04-03 WO disclosed
WO-1997010279-A1 RETROREFLECTIVE ARTICLE CONTAINING A POLYESTER POLYURETHANE BINDER LAYER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-03-20 WO disclosed
EP-0742244-A2 Durable polysulfide composition for optical material MITSUI TOATSU CHEMICALS, INC. (JP) 1996-11-13 EP disclosed
JP-H07247337-A PREPARATION OF THERMOPLASTIC RESIN, THERMOPLASTIC RESIN, AND STYRENE RESIN COMPOSITION DAINIPPON INK & CHEM INC 1995-09-26 JP disclosed
EP-0434079-B1 N,N'-hydrocarbylenebis(N-hals-substituted amic acid hydrazides) and their derivatives ATOCHEM NORTH AMERICA (US) 1995-09-20 EP disclosed
EP-0434080-A1 Derivatives of N-hals-substituted amic acid hydrazides ELF ATOCHEM NORTH AMERICA, INC. (US) 1991-06-26 EP disclosed
US-4918167-A Method of producing prepolymers from hydroxyalkyl lignin derivatives CENTER FOR INNOVATIVE TECHNOLOGY (US) 1990-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210186829-A1 OIL-IN-WATER EMULSION COMPRISING AN AMPHIPHILIC POLYMER NAPEPLD, PHOSPHO1, PLIN5 MIF 3811/4885ALDH1A1 4347/4885NOS1 2004/4885
US-10925815-B2 Oil-in-water emulsion comprising an amphiphilic polymer NAPEPLD, PHOSPHO1, PLIN5 MIF 3811/4885ALDH1A1 4347/4885NOS1 2004/4885
US-11273112-B2 Process for treating keratin fibers using a halochromic triarylmethane direct dye, an alkaline revealer and then an acidic eraser KRT18, DNER, PRKDC MIF 4753/4885ALDH1A1 797/4885NOS1 4559/4885
US-12109280-B2 Oil-in-water emulsion comprising an amphiphilic polymer NAPEPLD, PHOSPHO1, PLIN5 MIF 3811/4885ALDH1A1 4347/4885NOS1 2004/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.