Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL558395 | 0.72 | NOS1 (0.42) | ALDH1A1 | |
| SCHEMBL558182 | 0.72 | NOS1 (0.42) | — | |
| SCHEMBL395374 | 0.72 | GAA (0.33) | ALDH1A1 | |
| SCHEMBL16097856 | 0.69 | IDO1 (0.46) | — | |
| SCHEMBL558190 | 0.68 | AXL (0.47) | — | |
| SCHEMBL7258404 | 0.68 | GABRA1 (0.38) | ALDH1A1 | |
| SCHEMBL29662088 | 0.67 | NOS1 (0.55) | ALDH1A1 | |
| SCHEMBL647458 | 0.66 | NOS1 (0.50) | ALDH1A1 | |
| SCHEMBL555089 | 0.65 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL3079936 | 0.65 | BCHE (0.40) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071530-B | Fused pyrimidine piperidine ring derivatives, and preparation method and application thereof | 上海艾力斯医药科技股份有限公司 | 2021-08-17 | — | — | CN | disclosed |
| CN-109071530-A | Annelated pyrimidines piperidines ring derivatives and its preparation method and application | 上海艾力斯医药科技有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-107459519-A | Annelated pyrimidines piperidines ring derivatives and its preparation method and application | 上海艾力斯医药科技有限公司 | 2017-12-12 | — | — | CN | disclosed |
| CN-102421769-B | Vinyl indazolyl compounds | LILLY CO ELI (US) | 2014-04-02 | — | — | CN | disclosed |
| CN-102421769-B | Vinyl indazolyl compounds | LILLY CO ELI (US) | 2014-04-02 | — | — | CN | disclosed |
| EP-2427449-B1 | VINYL INDAZOLYL COMPOUNDS | LILLY CO ELI (US) | 2013-04-03 | — | — | EP | disclosed |
| US-8268869-B2 | Vinyl indazolyl compounds | ELI LILLY AND COMPANY (US) | 2012-09-18 | — | — | US | disclosed |
| US-8268869-B2 | Vinyl indazolyl compounds | ELI LILLY AND COMPANY (US) | 2012-09-18 | — | — | US | disclosed |
| US-8268869-B2 | Vinyl indazolyl compounds | ELI LILLY AND COMPANY (US) | 2012-09-18 | — | — | US | disclosed |
| CN-102421769-A | Vinyl indazolyl compounds | LILLY CO ELI (US) | 2012-04-18 | — | — | CN | disclosed |
| CN-102421769-A | Vinyl indazolyl compounds | LILLY CO ELI (US) | 2012-04-18 | — | — | CN | disclosed |
| EP-2427449-A1 | VINYL INDAZOLYL COMPOUNDS | Eli Lilly and Company (US) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010129509-A1 | VINYL INDAZOLYL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2010-11-11 | — | — | WO | disclosed |
| US-20100286209-A1 | VINYL INDAZOLYL COMPOUNDS | ELI LILLY AND COMPANY | 2010-11-11 | — | — | US | disclosed |
| US-20100286209-A1 | VINYL INDAZOLYL COMPOUNDS | ELI LILLY AND COMPANY | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286209-A1 | VINYL INDAZOLYL COMPOUNDS | VHL, IDH3B, IDH3A | ALDH1A1 466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.