SCHEMBL2500403

SCHEMBL2500403

O=C(Cc1ccccc1S(=O)(=O)c1ccccc1CC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 9/20 0.53
MMP12 P39900 9/20 0.53
MMP13 P45452 9/20 0.53
MMP14 P50281 9/20 0.53
MMP9 P14780 8/20 0.53
MMP1 P03956 7/20 0.53
MMP3 P08254 7/20 0.53
MMP8 P22894 6/20 0.53
MMP16 P51512 6/20 0.53
MAPT P10636 3/20 0.47
TDP1 Q9NUW8 3/20 0.47
KDM4E B2RXH2 3/20 0.47
MAPK1 P28482 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
MEN1 O00255 1/20 0.47
CYP3A4 P08684 1/20 0.47
HPGD P15428 1/20 0.47
ALOX15 P16050 1/20 0.47
CES1 P23141 1/20 0.47
KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6026006 0.86 MAPK1 (0.46) MMP2MMP12MMP13MMP14MMP9
SCHEMBL6026669 0.86 CA1 (0.54) MMP2MMP12MMP13MMP14MMP9
SCHEMBL3673843 0.85 L3MBTL1 (0.42) MMP2MMP12MMP13MMP14MMP9
SCHEMBL7196858 0.82 MAPT (0.61) MAPTTDP1KDM4EMAPK1SMN1; SMN2
SCHEMBL3672572 0.81 HSD11B1 (0.55) MMP2MMP12MMP13MMP14MMP9
SCHEMBL3669454 0.80 MAPT (0.49) MAPTTDP1KDM4EMAPK1SMN1; SMN2
SCHEMBL3669105 0.80 KMT2A (0.44) MAPTTDP1KDM4EMAPK1SMN1; SMN2
SCHEMBL3670848 0.80 MMP1 (0.45) MMP2MMP12MMP13MMP14MMP9
SCHEMBL3671243 0.80 MAOA (0.45) MMP2MMP12MMP13MMP14MMP9
SCHEMBL7619216 0.78 SRD5A2 (0.49) MMP2MMP12MMP13MMP14MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5994022-A BECOMES SOLUBLE IN ALKALI DEVELOPING SOLUTION BY ACTION OF AN ACID JSR CORPORATION (JP) 1999-11-30 US claimed
US-10421853-B2 Photosensitive gas generating agent and photocurable composition CANON KABUSHIKI KAISHA (JP) 2019-09-24 US disclosed
EP-2941781-B1 PHOTOSENSITIVE GAS GENERATING AGENT AND PHOTOCURABLE COMPOSITION CANON KK (JP) 2017-08-09 EP disclosed
US-20150368433-A1 PHOTOSENSITIVE GAS GENERATING AGENT AND PHOTOCURABLE COMPOSITION CANON KABUSHIKI KAISHA (JP) 2015-12-24 US disclosed
EP-2941781-A1 PHOTOSENSITIVE GAS GENERATING AGENT AND PHOTOCURABLE COMPOSITION Canon Kabushiki Kaisha (JP) 2015-11-11 EP disclosed
US-20150086755-A1 PHOTOCURED PRODUCT CANON KABUSHIKI KAISHA (JP) 2015-03-26 US disclosed
WO-2014136977-A1 PHOTOSENSITIVE GAS GENERATING AGENT AND PHOTOCURABLE COMPOSITION CANON KABUSHIKI KAISHA (JP) 2014-09-12 WO disclosed
WO-2013183468-A1 PHOTOCURED PRODUCT CANON KABUSHIKI KAISHA (JP) 2013-12-12 WO disclosed
US-8582210-B2 Lens and method for producing lens CANON KABUSHIKI KAISHA (JP) 2013-11-12 US disclosed
US-20110242672-A1 LENS AND METHOD FOR PRODUCING LENS CANON KABUSHIKI KAISHA (JP) 2011-10-06 US disclosed
WO-2000059494-A1 STYRYL SULFONE ANTICANCER AGENTS TEMPLE UNIVERSITY- OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2000-10-12 WO disclosed
US-6114086-A COMPRISING ALKALI-SOLUBLE RESIN, DISSOLUTION CONTROLLING AGENTS, PHOTOACID GENERATOR, SOLVENT; USED FOR THE MANUFACTURE OF SEMICONDUCTOR DEVICES OR INTEGRATED CIRCUITS JSR CORPORATION (JP) 2000-09-05 US disclosed
EP-1027330-A1 STYRYL SULFONE ANTICANCER AGENTS Temple University of the Commonwealth System of Higher Education (US) 2000-08-16 EP disclosed
US-5994022-A BECOMES SOLUBLE IN ALKALI DEVELOPING SOLUTION BY ACTION OF AN ACID JSR CORPORATION (JP) 1999-11-30 US disclosed
US-5916729-A A POSITIVE TONE TYPE REISTS CONSISTS OF A RESIN WHICH HAS AN ACIDIC FUNCTIONAL GROUP PROTECTED BY AN ACID DECOMPOSABLE GROUP AND IS HYDROLYZABLE, A PHOTOACID GENERATOR AND A SOLVENT MIXTURE OF ALKYL LACTATE WITH PROPYLENE GLYCOL ETHER JSR CORPORATION (JP) 1999-06-29 US disclosed
WO-1999018068-A1 STYRYL SULFONE ANTICANCER AGENTS TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 1999-04-15 WO disclosed
EP-0843220-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-05-20 EP disclosed
EP-0634696-B1 Chemically amplified resist composition JAPAN SYNTHETIC RUBBER CO LTD (JP) 1998-01-14 EP disclosed
US-5629135-A ALKALI-SOLUBLE RESIN, CROSSLINKER, PHOTOACID GENERATOR, SOLVENT JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-05-13 US disclosed
EP-0634696-A1 Chemically amplified resist composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1995-01-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150368433-A1 PHOTOSENSITIVE GAS GENERATING AGENT AND PHOTOCURABLE COMPOSITION PFN1, PFAS, FRG1 MMP2 4716/4885MMP12 4684/4885MMP13 4833/4885
US-10421853-B2 Photosensitive gas generating agent and photocurable composition PFN1, PFAS, FRG1 MMP2 4716/4885MMP12 4684/4885MMP13 4833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.