Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | F12 | P00748 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1741633 | 0.81 | LMNA (0.44) | KMT2AMEN1PLAUALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL28340528 | 0.80 | LMNA (0.43) | KMT2AMEN1PLAUALDH1A1LMNA | |
| SCHEMBL3058170 | 0.77 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1L3MBTL1SIGMAR1 | |
| SCHEMBL28899703 | 0.76 | ALDH1A1 (0.38) | KMT2AMEN1PLAUALDH1A1F2 | |
| SCHEMBL28899661 | 0.74 | ALDH1A1 (0.36) | KMT2AMEN1PLAUALDH1A1L3MBTL1 | |
| SCHEMBL725723 | 0.74 | ALDH1A1 (0.36) | KMT2AMEN1PLAUALDH1A1HTR3E | |
| SCHEMBL28899758 | 0.74 | ALDH1A1 (0.37) | KMT2AMEN1PLAUALDH1A1LMNA | |
| SCHEMBL28960083 | 0.74 | KMT2A (0.35) | KMT2AMEN1PLAUALDH1A1LMNA | |
| SCHEMBL18762979 | 0.74 | MEN1 (0.57) | KMT2AMEN1ALDH1A1L3MBTL1F2 | |
| SCHEMBL18762987 | 0.74 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1LMNAF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115414480-A | Dianhydrogalactitol in combination with radiation for treatment of non-small cell lung cancer and glioblastoma multiforme | 德玛医药 | 2022-12-02 | — | — | CN | disclosed |