Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | F12 | P00748 | 1/20 | 0.32 |
| ▸ | F7 | P08709 | 1/20 | 0.32 |
| ▸ | F3 | P13726 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 3/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3058170 | 0.80 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1L3MBTL1GAA | |
| SCHEMBL1741633 | 0.77 | LMNA (0.44) | ALDH1A1KMT2AMEN1L3MBTL1PLAU | |
| Hydrochloric Acid SCHEMBL28340528 | 0.75 | LMNA (0.43) | ALDH1A1KMT2AMEN1L3MBTL1BLM | |
| SCHEMBL30960118 | 0.75 | ALDH1A1 (0.40) | ALDH1A1KMT2AMEN1GAAMAPT | |
| SCHEMBL28899703 | 0.74 | ALDH1A1 (0.38) | ALDH1A1KMT2AMEN1MAPTHPGD | |
| Acetic Acid SCHEMBL27814143 | 0.74 | NPSR1 (0.41) | ALDH1A1KMT2AMEN1L3MBTL1NPSR1 | |
| SCHEMBL28899686 | 0.74 | KMT2A (0.36) | ALDH1A1KMT2AMEN1L3MBTL1F2 | |
| SCHEMBL725723 | 0.73 | ALDH1A1 (0.36) | ALDH1A1KMT2AMEN1F2F10 | |
| SCHEMBL28899661 | 0.73 | ALDH1A1 (0.36) | ALDH1A1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL18762979 | 0.72 | MEN1 (0.57) | ALDH1A1KMT2AMEN1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115414480-A | Dianhydrogalactitol in combination with radiation for treatment of non-small cell lung cancer and glioblastoma multiforme | 德玛医药 | 2022-12-02 | — | — | CN | disclosed |